Acinic cell tumor of the buccal mucosa; report of a case.

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A case of acinic cell tumor in the left buccal mucosa has been reported. The patient was 64-year-old female, admitted for evaluation of a mass in the left buccal mucosa. A soft mass measuring 3.0×1.8cm was noticed in the left buccal mucosa. After an incisional biopsy, the tumor was treated by wide local excision. One year and 3 months after the operation, she was well with no evidence of recurrence or metastasis of the tumor.<BR>Histologically, the tumor mainly consisted of serous-type cells including of a few vacuolated cells. Growth pattern of the tumor cells was a solid one. The tumor cells contained many basophilic granules in the cytoplasm, which were PAS-positive with diastase resistance and negative for mucicarmin staining. Ultrastructurally, the tumor cells generally consisted of large cells with abundant secretory granules which resembled serous cells of the normal acini. A few smaller tumor cells lacking secretory granules were also observed. Since the tumor showed slight atypia and no encapsulation, the tumor in this case was considered a low grade malignant. We support the hypothesis from the findings in this case that acinic cell tumor may represent a neoplasm of multipotential duct cells.
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