ビフィズス菌の生育に及ぼすpantethineの効果

概要

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The effects of pantethine (PaSS) on the growth of Bifidobacterium were examined. Lactobacillus acidophilus grew on both media containing either Ca-pantothenate (PaA) or PaSS, whereas Bifidobacterium grew only on the latter medium. The essential requirement of PaSS for the growth of Bifidobacterium seems to be explained from the fact that PaSS itself is the precursor of CoA and ACP. Therefore the insufficiency of PaSS has a direct influence on the cell growth. Further research indicated that glucose-6-phosphate dehydrogenase activity in PaSS-deficient cells was 26% of that in PaSS-rich cells. It was concluded that the insufficiency of PaSS was an initial factor for the decrease of the activity of glucose-6-phosphate dehydrogenase, the key enzyme for biosynthesis, and it in turn also resu1ted in the decrease of the cell growth.
社団法人日本農芸化学会の論文