酵母によるd-イソクエン酸の生成 (酵母の有機酸発酵に関する研究-3,4-)

概要

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A yeast strain which was productive solely of an unknown organic acid from sugars as well as from hydrocarbons in shaking cultures was isolated from the air of the circumference of laboratory. This particular yeast was identified as Candida brumptii Langeron et Guerra. Examinations on the different yeast strains which were selected before as the citric acid producer showed that they all had an ability to produce the same unknown acid besides citric acid from various carbon sources under aerobic conditions. The unknown acid was isolated as its lactone from the cultures of the said Candida brumptii as well as from those of two citric acid producing yeasts, Candida guilliermondii var. membranaefaciens and Candida lipolytica. The lactone thus obtained was identified physico-chemically as d-isocitric acid lactone, revealing that the unknown acid itself is nothing but d-isocitric acid (DsLg- or threo-Ds isocitric acid).
社団法人日本農芸化学会の論文