Solubilization of Testosterone 5α-Reductase from Nuclear Fraction of Rat Ventral Prostate
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概要
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It was confirmed that the nuclear testosterone 5α-reductase was attached to membrane fraction as observed by Moore and Wilson (1972) in rat ventral prostate. Testosterone 5α-reductase of the nuclear membrane fraction was partially solubilized by phospholipase A, and overall 20 fold purification was attained. Optimum pH, pyridine nucleotide requirement and time course of the reaction of the solubilized enzyme were examined.
- 社団法人 日本内分泌学会の論文
著者
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KURIHARA Hiroshi
Department of Pharmacology, Tohoku University Graduate School of Medicine
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SHIDA KEIZO
Department of Urology, Gunma University School of Medicine
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FURUYA NOBUO
Department of Urology, Gunma University School of Medicine
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Shimazaki Jun
Department Of Ophthalmology School Of Medicine Keio University
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OHKI YUMIKO
Department of Urology, Gunma University School of Medicine
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SHIMAZAKI JUN
Department of Dermatology, School of Medicine, Chiba University
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SHIDA KEIZO
Department of Urology School of Medicine, Gunma University
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