Absence of Response of Chick Embryonic Limb to the Growth Stimulatory Effect of Parathyroid Hormone <I>In Vitro</I> after Exposure to 6-Aminonicotinamide <I>In Ovo</I>
スポンサーリンク
概要
- 論文の詳細を見る
The biochemical effect of a nicotinamide analogue, 6-aminonicotinamide (6-AN), on developing chick embryonic femur was studied. Growth of femur from 9-day-old embryos that had been exposed to 6-AN for 5 days <I>in ovo</I> was not stimulated by PTH in an <I>in vitro</I> culture system. PTH caused a much smaller increase in the cyclic-AMP content in 6-AN-treated femur than in control femur. However, dibutyryl cyclic-AMP stimulated growth of 6-AN-treated femur. A defect in response of 6-AN-treated femur to the growth stimulating action of PTH may explain the production of micromelia by 6-AN.
- 社団法人 日本内分泌学会の論文
著者
-
Endo Hiroyoshi
Department Of Physiological Chemistry Faculty Of Pharmaceutical Sciences Teikyo University
-
Tanuma Sei-ichi
Department Of Biochemistry Faculty Of Pharmaceutical Science Science University Of Tokyo
-
Kawashima Kohtaro
Department Of Physiological Chemiustry Faculty Of Pharmaceutical Sciences Teikyo University
-
Kawashima Kohtaro
Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Teikyo University
関連論文
- Enhancement of paclitaxel-induced apoptosis in HER2-overexpressing human breast cancer cells by a pertuzumab mimetic peptide, HRAP(MEDICAL BIOTECHNOLOGY)
- Glycogen Synthase Kinase-3β2 Has Lower Phosphorylation Activity to Tau than Glycogen Synthase Kinase-3β1
- Amyloid Precursor Protein Binding Protein Fe65 Is Cleaved by Caspases during DNA Damage-Induced Apoptosis
- Development of HER2-antagonistic peptides as novel anti-breast cancer drugs by in silico methods
- Genomic Drug Discovery for Apoptosis Regulation Using a New Computer Screening Amino Acid Complement Wave Method(Mitochondria and Neuroprotection)
- The Involvement of ATP Produced via (ADP-Ribose)_n in the Maintenance of DNA Replication Apparatus during DNA Repair(Molecular and Cell Biology)
- Oral dimethyl sulfoxide for systemic amyloid A amyloidosis complication in chronic inflammatory disease : a retrospective patient chart review
- Checkpoint Kinase 1 Is Cleaved in a Caspase-Dependent Pathway during Genotoxic Stress-Induced Apoptosis(Molecular and Cell Biology)
- Two-Dimensional Localization Effect with Spin-Orbit Scattering in Arsenic Doped Polycrystalline Silicon Films
- A Hall Element Yielding a Precise Field-Linear Hall Voltage up to a High-Field Region : Semiconductors and Semiconductor Devices
- BIOLOGICAL IMPLICATIONS OF APOPTOSIS/APOBIOSIS IN SENESCENCE AND LIFE-SPAN
- Innate Apoptosis of Human B Lymphoblasts Transformed by Epstein-Barr Virus : Modulation by Cellular Immortalization and Senescence
- Structural Phase Transition in Stage 2 SbCl_5-Graphite Intercalation Compound
- New Superconducting Phase in Potassium Amalgam Doped Fullerenes
- Induced Torque of SbCl_5-Graphite Intercalation Compounds
- Magnetic Susceptibility of SbCl_5-Graphite Intercalation Compounds
- Bi_Sb_ 合金の熱流磁気効果の磁場依存性
- De Haas-van Alphen Effect of SbCl_5-Graphite Intercalation Compounds.I
- De Haas-van Alphen Effect of SbCl_5-Graphite Intercalation Compounds.II
- Microgravity generated by space flight has little effect on the growth and development of chick embryonic bone
- Subcutaneous Arginine Administration Causes Apoptosis of Rat Pancreas
- DNA FRAGMENTATION IN APOPTOSIS
- Cladribine Enhances Apoptotic Cell Death in Lung Carcinoma Cells Over-Expressing DNase γ
- Effects of KCA-012 on Bone Metabolism in Organ Culture
- Stimulative Effect of High-level Hypergravity on Differentiated Functions of Osteoblast-like Cells
- Bidirectional Effects of Hypergravity on the Cell Growth and Differentiated Functions of Osteoblast-Like ROS17/2.8 Cells
- Improvement by Exogenous Cyclic AMP of Hereditary Vasopressin-Resistant Diuresis in Mice with Normal Adenyl Cyclase System of the Kidney Cells
- Level of Newly Synthesized Cyclic AMP in the Isolated Rat Kidney Cells and Its Changes by Vasopressin
- Effect of Hydrocortisone on Hela Cells with Special Reference to the RNA Metabolism
- Direct Regulation of Bone Resorption of Chick Embryonic Femur in Organ Culture by the Change of Calcium or Phosphate ion Concentration in the Medium
- Selective Activation of Diaphyseal Chondrocytes by Parathyroid Hormone, Calcitonin and N6, O2-Dibutyryl Adenosine 3, 5-Cyclic Monophosphoric Acid in Proteoglycan Synthesis of Chick Embryonic Femur Cultivated In Vitro
- Growth Stimulative Effect of Parathyroid Hormone, Calcitonin and N6, O2-Dibutyryl Adenosine 3, 5-Cyclic Monophosphorie Acid on Chick Embryonic Cartilage Cultivated in a Chemically Defined Medium
- Absence of Response of Chick Embryonic Limb to the Growth Stimulatory Effect of Parathyroid Hormone In Vitro after Exposure to 6-Aminonicotinamide In Ovo
- High prevalence of Sulfadoxine/pyrimethamine resistance alleles in Plasmodium falciparum parasites from Bangladesh
- Synthesis of Epidermal Specific Proteins Selectively Stimulated by Hydrocortisone in the Chick Embryonic Skin Growing in a Chemically Defined Medium
- Effect of Hormones on the Chondroitin Sulfate Metabolism of Chick Embryo Femora Growing in Vitro. 2. Differential Effect of Cortisol on Chondroitin Sulfate Synthesis in the Cartilagenous Bones Growing in Various Natural and Synthetic Media
- Effects of KCA-098 on Bone Metabolism: Comparison with Those of Ipriflavone.
- Enhanced Diffusion of Implanted Arsenic in Silicon at an Early Stage of Annealing