Mosapride Citrate for Colonoscopy Preparation with Lavage.
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概要
- 論文の詳細を見る
Background & Aims : Prokinetics have been used in combination with polyethylene glycol electrolyte lavage solution (PEG-ELS) to reduce the volume of lavage solution and to ensure the preparation. However, prokinetics sometimes accompany troublesome side effects including fatal ones. The aim of this study is to elucidate the usefulness of mosapride citrate, which has fewer side effects, for colonoscopy lavage preparation.<BR>Methods : Eighty-two patients were randomly assigned to receive 2, 000 ml of PEG-ELS with sennoside (control group) or 1, 500 ml of PEG-ELS with sennoside and mosapride citrate (mosapride group). Colonoscopists blinded to group assignment scored the adequacy of colon cleansing. Time to lavage solution ingestion, time and number of motions to the appearance of clear excretion, and side effects were recorded.<BR>Results and Conclusions : The mosapride group had a favorable trend in the overall colon cleansing and a significant superiority in the residual foam over the control group. Side effects had a tendency to be less frequent in the mosapride group. Time to lavage solution ingestion was significantly reduced in the mosapride group. Mosapride citrate coadministered with sennoside and 1500 ml of PEG-ELS is applicable to bowel preparation with favorable colon cleansing and good patient acceptability.
- 北関東医学会の論文
著者
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Mori Masatomo
Department Of Internal Medicine And Molecular Science Graduate School Of Medicine Gunma University
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Okamura Shinichi
Department Of Medical Informatics And Decision Sciences School Of Medicine Gunma University
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Sakamoto Teruhiko
Department Of Clinical Laboratory Tokyo Women's Medical University Medical Center East:departme
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Iesaki Keigo
Department Of Gastroenterology And Hepatology Saiseikai Maebashi Hospital
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Nagashima Mamiko
Department Of Gastroenterology Maebashi North Hospital
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Kobayashi Ryota
Department Of Applied Chemistry Faculty Of Science And Engineering Chuo University
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Yoshida Makoto
Department Of Biology Faculty Of Science University Of Kochi
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Ishikawa Takeshi
Department Of Chemistry And Materials Engineering Faculty Of Chemistry Materials And Bioengineering
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Iizuka Haruhisa
Department Of Endoscopy And Endoscopic Surgery Shirakawa Clinic
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Sakamoto Teruhiko
Department of Internal Medicine, Gunma University School of Medicine
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Ohmae Yoshio
Department of Internal Medicine, Gunma University School of Medicine
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Sagawa Toshihiko
Department of Internal Medicine, Gunma University School of Medicine
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Kudo Tomohiro
Department of Internal Medicine, Gunma University School of Medicine
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Masuo Takashige
Department of Internal Medicine, Gunma University School of Medicine
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Marubashi Kyoko
Department of Internal Medicine, Gunma University School of Medicine
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Oshimoto Hirokazu
Department of Internal Medicine, Gunma University School of Medicine
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Motegi Kenta
Department of Internal Medicine, Gunma University School of Medicine
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Okamura Shinichi
Department of Internal Medicine, Gunma University School of Medicine
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Ishikawa Takeshi
Department of Internal Medicine, Gunma University School of Medicine
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Sakamoto Teruhiko
Department of Clinical Laboratory and Endoscopy, Tokyo Women's Medical University, Medical Center East
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Nagashima Mamiko
Department of Internal Medicine, Gunma University School of Medicine
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Mori Masatomo
Department of Internal Medicine, Gunma University School of Medicine
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ISHIKAWA TAKESHI
Department of Chemical Engineering, Faculty of Engineering, Tokyo Metropolitan University
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Okamura Shinichi
Department of Gastroenterology, Toyohashi Municipal Hospital
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