Gastric Yolk Sac Tumor Complicated with Beta-Human Chorionic Gonadotropin-Producing Metastases
スポンサーリンク
概要
- 論文の詳細を見る
This report describes the case of 74-year-old man who had a gastric yolk sac tumor complicated with beta human chorionic gonadotropin (βhCG) producing metastases. He was a heavy drinker. He was admitted to the hospital for abdominal pain and fullness. Based on computed tomography and gastric endoscopy he was diagnosed to have gastric cancer that had metastasized to the liver, lung and lymph nodes. The level of serum alpha fetoprotein (AFP) was high at 523 ng/mL. He died of multiorgan failure six days after admission. The autopsy revealed the stomach tumor to be an AFP-positive yolk sac tumor. Lymph node metastases showed the same characteristics as the stomach tumor. However, the lesions on the liver and lung were negative for AFP and positive for hCG. The yolk sac tumor seemed to have retrodifferentiated to form an hCG-producing tumor in the metastatic lesions. A gastric yolk sac tumor is extremely rare and only eight cases of gastric yolk sac tumors have been previously reported in the literature. To avoid a misdiagnosis, careful attention should be paid to the above-mentioned morphological features and immunohistochemical findings, in addition to the clinical findings.
- 社団法人 日本内科学会の論文
著者
-
Mori Masatomo
Department Of Internal Medicine And Molecular Science Graduate School Of Medicine Gunma University
-
Ban Satoshi
Department Of Clinical Laboratories Gunma University School Of Medicine
-
Yoshida Katsue
Department Of Pathology And Clinical Laboratories Kiryu Welfare General Hospital
-
Tahara Hiroki
Department Of Medicine And Molecular Science Gunma University School Of Medicine
-
Maruta Sakae
Department of Internal Medicine, Kiryu Kosei General Hospital
-
Hirokawa Tomoyuki
Department Of Medicine And Molecular Science Gunma University Graduate School Of Medicine
-
Takagi Hitoshi
Department Of 1st Internal Medicine Gunma University School Of Medicine
-
Naganuma Atsushi
Department Of Medicine And Molecular Science Gunma University Graduate School Of Medicine
-
Oyama Tatsuya
Department of Internal Medicine, Kiryu Kosei General Hospital
-
Naganuma Atsushi
Department of Internal Medicine, Kiryu Kosei General Hospital
関連論文
- FEASIBILITY OF ENDOSCOPIC SUBMUCOSAL DISSECTION FOR ELDERLY PATIENTS WITH EARLY GASTRIC CANCERS AND ADENOMAS
- Type 2 Diabetes Mellitus Complicated with Smoldering Myeloma and Non-alcoholic Steatohepatitis
- B-Cell Lymphoma Associated with Sjogren's Syndrome among Japanese Patients : A Clinicopathologic and Immunohistochemical Study of 15 Cases
- Randomized, double-blind, placebo-controlled trial of bovine lactoferrin in patients with chronic hepatitis C
- Deterioration of Retinopathy After Starting Interferon Therapy for Chronic Hepatitis C with Diabetic Triopathy
- Secondary Hemochromatosis Accompanied by Diabetes Mellitus and Hypogonadism.
- Seroconversion of Glutamic Acid Decarboxylase Antibodies in a Patient Initially Diagnosed as Having Type 2 Diabetes Mellitus
- Metformin Use in an Obese Diabetic Patient from Weeks 1 to 21 of Pregnancy.
- Sarcoid Granulomatous Interstitial Nephritis Accompanied by Type 2 Diabetes Mellitus
- Clinicopathological Features of Patients with Bronchial-Associated Lymphoid Tissue Lymphoma
- Correlation of angiogenesis with ^F-FMT and ^F-FDG uptake in non-small cell lung cancer
- Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in early stage squamous cell carcinoma of the lung
- L-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms
- Reactive follicular hyperplasia in the lymph node lesions from systemic lupus erythematosus patients: A clinicopathological and immunohistological study of 21 cases
- Occurrence of Monocytoid B-cells in Reactive Lymph Node Lesions
- A Simple Method to Induce Differentiation of Murine Bone Marrow Mesenchymal Cells to Insulin-producing Cells Using Conophylline and Betacellulin-delta4
- Prader-Willi Syndrome with Elevated Follicle Stimulating Hormone Levels and Diabetes Mellitus
- Low burden of a JAK2-V617F mutated clone in monoclonal haematopoiesis in a Japanese woman with Budd-Chiari syndrome
- A Patient with Classic Severe Primary Hyperparathyroidism in Whom both Tc-99m MIBI Scintigraphy and FDG-PET Failed to Detect the Parathyroid Tumor
- Administration time difference of candesartin effect on albuminuria in type 2 diabetic patients
- Contribution of Fasting and Postprandial Hyperglycemia to Hemoglobin A_ in Insulin-Treated Japanese Diabetic Patients
- Rapid Effect of nCPAP Therapy on Circulating Plasma Leptin in OSAS Patients
- Rheumatoid Arthritis Preceded by Interstitial Pneumonia Associated with Myelodysplastic Syndrome : A Case Report
- Pulmonary Alveolar Proteinosis Manifested by Patchy Peripheral Air-space Disease : A Case Report
- Role of Vitronectin Receptor-Type Integrins and Osteopontin in Ischemia-Induced Retinal Neovascularization
- Primary malignant lymphoma of the intestine : Clinicopathologic and immunohistochemical studies of 39 cases
- Dubin-Johnson 症候群患者に認めたABCC2遺伝子の部分欠損(exon 7 全域)例
- Imprint Cytology of Large B-cell Lymphoma with High Content of Epithelioid Cells : A Report of Two Cases
- Florid Reactive Follicular Hyperplasia in Elderly Patients : A Clinicopathological Study of 23 Cases
- Nonalcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery (LRYGB) in comparison to non-Japanese patients
- Adefovir dipivoxil monotherapy is a sufficiently effective treatment modality for Japanese patients with lamivudine-resistant chronic hepatitis B
- Massive Hemoptysis Due to Pulmonary Tuberculosis
- No Way of Telling What Lies Ahead in One's Life
- Loss of Consciousness and Hypokalemia in an Elderly Man with a Mutation of the Thiazide-sensitive Na-Cl Cotransporter Gene
- Clinical and Immunological Characterization of Patients with Systemic Sclerosis Overlapping Primary Biliary Cirrhosis : A Comparison with Patients with Systemic Sclerosis Alone
- Expression of Thyroid Hormone Receptor Isoforms Down-regulated by Thyroid Hormone in Human Medulloblastoma Cells
- Gastroptosis is Associated with Less Dyspepsia, Rather than a Cause of Dyspepsia, in Japanese Persons
- Photo-electrochemical Deposition of Platinum on TiO_2 with Resolution of Twenty Nanometers using a Mask Elaborated with Electron-Beam Lithography
- High Prevalence of Gastroesophageal Reflux Disease with Minimal Mucosal Change in Asthmatic Patients
- A Proton Pump Inhibitor, Lansoprazole, Ameliorates Asthma Symptoms in Asthmatic Patients with Gastroesophageal Reflux Disease
- High Seroprevalence of Helicobacter pylori in Chronic Bronchitis among Chinese Population
- Helicobacter pylori Seroprevalence in Patients with Mild Asthma
- Development and evaluation of FSSG : frequency scale for the symptoms of GERD
- NUMERICAL MODIFICATION OF THE LOS ANGELES CLASSIFICATION OF GASTROESOPHAGEAL REFLUX DISEASE FAILS TO DECREASE OBSERVER VARIATION
- A Novel Splice Variant of the Nuclear Coactivator p120 Functions Strongly for Androgen Receptor : Characteristic Expression in Prostate Disease
- Photodynamic Therapy for Typical Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy : A 30-Month Multicenter Study in Hyogo, Japan
- Primary Bilateral Adrenal Diffuse Large B-cell Lymphoma Demonstrating Adrenal Failure
- Solvent Extraction of Iron(II) and Iron(III) as Anionic Thiocyanate Complexes with Tetrabutylammonium Ions into Chloroform
- Herbal Medicine, Hachimi-jio-gan, and Its Component Cinnamomi Cortex Activate the Peroxisome Proliferator-activated Receptor Alpha in Renal Cells
- Glucose-Dependent Insulinotropic Polypeptide Induced Growth Hormone Secretion in Acromegaly
- A CASE OF CA19-9-PRODUCING ADENOCARCINOMA OF THE REMNANT STOMACH RESEMBLING GASTRITIS CYSTICA POLYPOSA
- Enteropathy-type T-cell Lymphoma that was Pathologically Diagnosed as Celiac Disease
- New Frontiers in Gut Nutrient Sensor Research : Monosodium L-Glutamate Added to a High-Energy, High-Protein Liquid Diet Promotes Gastric Emptying : a Possible Therapy for Patients With Functional Dyspepsia
- Nesfatin-1 : An Overview and Future Clinical Application
- Leptin Resistance and Obesity
- Artificial Neural Network for Predicting the Toxicity of Organic Molecules
- 症例報告 A Case of Postmenopausal Lymphangioleiomyomatosis without Signs of Aggravation in the Follow-up Period
- CLINICAL CHARACTERISTICS AND TREATMENT FOR PATIENTS PRESENTING WITH BLEEDING DUODENAL VARICES
- Aspiration Pneumonia Resulting from a Peanut
- STRICTURE AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION FOR EARLY GASTRIC CANCERS AND ADENOMAS
- A satiety molecule, Nesfatin-1 in the hypothalamus
- Hepatocellular Carcinoma with Peritoneal Dissemination which was Regressed during Vitamin K2 and Vitamin E Administration
- Effect of Fiber Length on Mechanical Properties of "Green" Composites Using a Starch-Based Resin and Short Bamboo Fibers(Green Composites)
- Prediction of cerebral infarct sizes by cerebral blood flow SPECT performed in the early acute stage
- Marked Eosinophilia as the First Manifestation of Sclerosing Cholangitis
- Attenuated expression of menin and p27^ in an aggressive case of multiple endocrine neoplasia type 1 (MEN1) associated with an atypical prolactinoma and a malignant pancreatic endocrine tumor
- A retrospective cohort study of partial splenic embolization for antiviral therapy in chronic hepatitis C with thrombocytopenia
- Nesfatin-1 enhances glucose-induced insulin secretion by promoting Ca^ influx through L-type channels in mouse islet β-cells
- Infinitesimal isometries of frame bundles with natural Riemannian metric
- Effect of Aging on Acoustic Emission Behaviour During Tensile Deformation of an Al-Li-Cu-Mg-Zr Alloy
- Attainment of glycaemic goals by step-up therapy with biphasic insulin aspart-70/30 in Japanese type 2 diabetic patients
- Molecular Mechanisms of Retinal Neovasculaization in Diabetic Retinopathy
- Changes in Blood Levels of Estradiol-17β before Induced Ovulation, Leading to Luteal Hypoplasia in Cows
- Non existence of isometric free T^2 action to compact positively curved manifolds
- Crosstalk of thyroid hormone receptor and liver X receptor in lipid metabolism and beyond
- Orthodox Sometimes Generates Paradox
- KCNJ5 mutations in aldosterone- and cortisol-co-secreting adrenal adenomas
- Dilated Cardiomyopathy as a Presenting Feature of Cushing's Syndrome
- Acute Respiratory Failure Associated with Miliary Tuberculosis Successfully Treated with Sivelestat Sodium Hydrate
- Mosapride Citrate for Colonoscopy Preparation with Lavage.
- Systemic Sclerosis after Interferon Alphacon-1 Therapy for Hepatitis C
- Gastric Yolk Sac Tumor Complicated with Beta-Human Chorionic Gonadotropin-Producing Metastases
- Reversible Posterior Leukoencephalopathy Syndrome after Carboplatin and Paclitaxel Regimen for Lung Cancer
- An Obese Patient with Slowly Progressive Type 1 Diabetes Diagnosed by Ketoacidosis
- The anti-apoptotic effect of fucoxanthin on carbon tetrachloride-induced hepatotoxicity
- A case of thyroid storm with a markedly elevated level of circulating soluble interleukin-2 receptor complicated by multiple organ failure and disseminated intravascular coagulation syndrome