Effects of a crude extract of a marine dinoflagellate, containing dimethyl-.BETA.-propiothetin, on HClethanol-induced gastric lesions and gastric secretion in rats.
スポンサーリンク
概要
- 論文の詳細を見る
A crude extract of <I>Crypthecodinium cohnii</I> and its main component, dimethyl-β-propiothetin, significantly and dose-dependently protected the gastric mucosa against HCI-ethanol-induced lesions in rats. Since indomethacin pretreatment reduced the protective effect to some extent, endogenous prostaglandins might be partly involved in the mechanism of action. Both the crude extract and dimethyl-β-propiothetin significantly increased gastric secretion.
- 公益社団法人 日本薬理学会の論文
著者
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Okabe Susumu
Department Of Applied Pharmacology Kyoto College Of Pharmacy
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OGIHARA Yoshiyasu
Department of Applied Pharmacology, Kyoto Pharmaceutical University
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ISHIDA Yusaburo
Department of Fisheries, Faculty of Agriculture, Kyoto University
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