Effect of sizofilan, an immunomodulator, on hepatic microsomal mixed-function oxidase activities in rats.
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概要
- 論文の詳細を見る
Mixed-function oxidase activities of hepatic microsomal preparations from rats were examined after intraperitoneal administration of sizofilan (SPG), an immunomodulator. Repeated doses of SPG (3 mg/kg/12 hr, 4 times) depressed the hepatic cytochrome P-450 content and the activities of aminopyrine N-demethylase and aniline hydroxylase.
- 公益社団法人 日本薬理学会の論文
著者
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TAKAYANAGI Yoshio
Department of Pharmacology and Toxicology, Cancer Research Institite, Tohoku Phamaceutical Universit
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KOIWAI Kimiko
Department of Pharmacology and Toxicology, Cancer Research Institute, Tohoku College of Pharmacy
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Ishikawa Masaaki
Department Of Clinical Pharmacotherapeutics Tohoku Pharmaceutical University
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Koiwai Kimiko
Department Of Clinical Pharmacotherapeutics Tohoku Pharmaceutical University
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Yomogida Shin
Department Of Host Defense And Biochemical Research Juntendo University School Of Medicine
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Sasaki Ken-ichi
Department Of Chemistry Faculty Of Science Hiroshima University
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SASAKI Ken-ichi
Department of Pharmacology and Toxicology, Cancer Research Institute, Tohoku College of Pharmacy
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SHIBA Yoshihiro
Department of Pharmacology and Toxicology, Cancer Research Institute, Tohoku College of Pharmacy
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