Myocardial perfusion and left ventricular performance during exercise-induced ST-segment depression in apparently healthy subjects.
スポンサーリンク
概要
- 論文の詳細を見る
Ischemic-like ST-segment depression seen during exercise in apparently healthy subjects has previously been noted, but the cause of this change is unknown. The aim of this study was to investigate the pathophysiology of this electrocardiographic change. Ten healthy subjects who developed an electrocardiographic "ischemic" pattern of ST change during treadmill exercise testing were studied. All subjects underwent both thallium-201 myocardial perfusion imaging and radionuclide angiocardiography at rest and during exercise at a time when abnormal ST changes appeared, and demonstrated a normal homogeneous pattern of thallium-201 distribution on both rest and exercise images. Overall, left ventricular ejection fraction rose from 0.60±0.06 (mean±SD) at rest to 0.65±0.07 with exercise. None of the subjects had regional wall motion abnormalities at rest or during exercise.These results are different from the findings observed in patients with coronary heart disease and angina pectoris in whom regional abnormalities in both perfusion and left ventricular performance have been noted during exercise. Therefore it would seem that myocardial ischemia is not likely to be a tenable explanation for the electrocardiographic "ischemic" changes in these apparently healthy subjects.
- International Heart Journal刊行会の論文
著者
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Ando Joji
Department Of Biomedical Engineering Faculty Of Medicine University Of Tokyo
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Miyamoto Atsushi
Department Of Cardiovascular Medicine School Of Medicine Hokkaido University
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Kobayashi Takeshi
Department Of Biological Chemistry College Of Bioscience And Biotechnology Chubu University
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Kanamori Katsushi
Department Of Cardiovascuiar Medicine Hokkaido University Schooi Of Medicine Hokkaido University
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Matsumura Naoya
Department Of Cardiology Hakodate Central General Hospital
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Nishijima Hirotaka
Department Of Cardiovascular Medicine Hokkaido University School Of Medicine
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Yasuda Hisakazu
Department O F Cardiovascular Medicine Hokkaido University School Of Medicine
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YASUDA Hisakazu
Department of Cardiovascular Medicine, Hokkaido University, School of Medicine
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NISHIJIMA Hirotaka
Department of Cardiovascular Medicine, Hokkaido University, School of Medicine
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