Alterations in myocardial perfusion during painless ST-segment depression in patients with angina pectoris.
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概要
- 論文の詳細を見る
In order to determine whether painless ST changes represent myocardial ischemia, we studied regional myocardial perfusion in patients with angina pectoris who showed painless ST-segment depression during a treadmill exercise test.Twenty-one patients were evaluated by myocardial imaging using thallium-201 injected intravenously during exercise when painless ST-segment depression was evident. The same examination was repeated in 5 of the above patients when they showed ST-segment depression with chest pain. Myocardial images obtained during painless ST-segment depression revealed perfusion defects in 15 of 21 patients (71%). Images obtained during STsegment depression with chest pain showed perfusion defects in all 5 patients (100%) including 3 patients who demonstrated no defects during painless ST-segment depression. In these 5 patients, the ST-segment depression associated with pain was significantly greater than that without pain (3.4±1.1 vs 2.1±1.1mm, p<0.01).These results suggest that the majority of episodes of painless ST-segment depression occurring during exercise are accompanied by regional myocardial perfusion abnormalities and that transient painless ST-segment depression in patients with angina pectoris might represent less severe myocardial ischemia.
- International Heart Journal刊行会の論文
著者
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Kojima Shunichi
Department Of Cardiovascular Medicine Hokkaido University School Of Medicine
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Ando Joji
Department Of Biomedical Engineering Faculty Of Medicine University Of Tokyo
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Miyamoto Atsushi
Department Of Cardiovascular Medicine School Of Medicine Hokkaido University
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Kobayashi Takeshi
Department Of Biological Chemistry College Of Bioscience And Biotechnology Chubu University
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Kanamori Katsushi
Department Of Cardiovascuiar Medicine Hokkaido University Schooi Of Medicine Hokkaido University
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Matsumura Naoya
Department Of Cardiology Hakodate Central General Hospital
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Yasuda Hisakazu
Department O F Cardiovascular Medicine Hokkaido University School Of Medicine
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KANAMORI Katsushi
Department of Cardiovascular Medicine, Hokkaido University, School of Medicine
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MIYAMOTO Atsushi
Department of Cardiovascular Medicine, Hokkaido University, School of Medicine
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MATSUMURA Naoya
Department of Cardiovascular Medicine, Hokkaido University, School of Medicine
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KOYA Tetsuo
Department of Cardiovascular Medicine, Hokkaido University, School of Medicine
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