BENEFICIAL EFFECT OF STOPPING SMOKING ON FUTURE CARDIAC EVENTS IN MALE SMOKERS WITH PREVIOUS MYOCARDIAL INFARCTION

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概要

• 論文の詳細を見る

• We assessed the effect of stopping smoking on future cardiac events (cardiac death and non-fatal myocardial infarction (MI)) in 90 male smokers with previous MI by a prospective follow-up study. At the time of enrollment, the patients were divided into 2 groups according to their current smoking status (Group A: those who had stopped smoking (n=60), and Group B: those who were still smoking (n=30)). Follow-up was performed prospectively by annual postal questionnaires. During the mean follow-up period of 3.1 ± 1.4 years, 13 cardiac events (11 cardiac deaths and 2 cases of non-fatal MI) occurred in the 87 evaluable patients. The cardiac event rates in Groups A and B were 8.5% and 28.6%, respectively, and the relative risk was 3.4 (Group A vs B, p<0.05) by univariate analysis. The relative risk using multivariate analysis (Cox) was also statistically significant (3.1, p<0.05). HDL-cholesterol was significantly lower in Group B than in Group A, but other coronary risk factors apart from smoking were not significantly different between the two groups. At the end of the follow-up period, 89.8% of the patients in Group A remained nonsmokers and 21% of the patients in Group B had stopped smoking. Conclusion: Stopping smoking significantly reduced the risk of future cardiac events in male smokers with previous MI. This prospective follow-up study demonstrated that a significant reduction in the risk of future cardiac events could be achieved by stopping smoking in this group of patients.

• 社団法人日本循環器学会の論文
• 1992-03-20

著者

• Nishijima Hirotaka

  Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine

• Nishijima Hirotaka

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine Sapporo Japan

• Kojima Shunichi

  Department of Medicine, National Cardiovascular Center

• YASUDA HISAKAZU

  Department of Cardiovascular Medicine, Hokkaido University School of Medicine

• Yasuda Hisakazu

  Hokkaido University

• Kojima Shunichi

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine

• Yasuda Hisakazu

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine Sapporo Japan

• Yasuda Hisakazu

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine

• Yasuda Hisakazu

  Department Of Cardiology Hokkaido University School Of Medicine Sapporo

• SATO ISAO

  Department of Cardiovascular Medicine Hokkaido University School of Medicine, Sapporo, Japan

• MATSUMURA NAOYA

  Department of Cardiovascular Medicine Hokkaido University School of Medicine, Sapporo, Japan

• NISHIDA MASAYUKI

  Department of Cardiovascular Medicine Hokkaido University School of Medicine, Sapporo, Japan

• OKITA KOHICHI

  Department of Cardiovascular Medicine, Hokkaido University School of Medicine

• Yasuda Hisakazu

  Department Of Cardiovascular Medicine Hokkaido Univcrsity

• Yasuda Hisakazu

  The Department Of Cardiovascular Medicine Hokkaido University School Of Medicine

• Sato Isao

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine Sapporo Japan

• Okita Kohichi

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine

• Yasuda Hisakazu

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine Sapporo

• Matsumura Naoya

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine Sapporo Japan

• Matsumura Naoya

  Department Of Cardiology Hakodate Central General Hospital

• Nishida Masayuki

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine Sapporo Japan

• Nishida Masayuki

  Department Of Cardiovascular Medicine Hokkaido University School Of Med

• Nishijima Hirotaka

  Department Of Cardiovascular Medicine Hokkaido University School Of Medicine

• Yasuda Hisakazu

  Department Of Cardiology Hokkaido University School Of Medicine

• Sato Isao

  Department Of Anesthesiology Koshigaya Hospital Dokkyo University School Of Medicine

• Yasuda Hisakazu

  Department O F Cardiovascular Medicine Hokkaido University School Of Medicine

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