Cation Transport of Red Blood Cells from Hypertensive Patients in Japan
スポンサーリンク
概要
- 論文の詳細を見る
This study was performed to determine whether there is any difference in cation transport of red blood cells from normotensive subjects and hypertensive patients in Japan. Net Na+ efflux and net K+ influx rates were measured in sodium-loaded red cells from 19 normotensive subjects, 22 essential hypertensive patients, and 8 secondary hypertensive patients. The ratio of Na+/K+ net fluxes and the net cation flux rate were compared between these groups. The ratio of Na+/K+ net fluxes was significantly lower in essential hypertensive patients than in normotensive subjects. Parameters such as age, sex, blood pressure, plasma renin activity, and plasma aldosterone concentration were also examined in 2 groups of essential hypertensive patients, divided on the basis of their Na+/K+ net fluxes. However, there is no significant difference between the groups. These results suggest that the ratio of cation flux is related to hypertension independently of these parameters.
著者
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Kimura Genjiro
Department Of Cardio-renal Medicine And Hypertension Nagoya City University Graduate School Of Medic
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Osada Tsuguo
Department Of Medicine National Cardiovascular Center
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YOKOUCHI MASATOSHI
Department of Internal Medicine, National Cardiovascular Center
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DEGUCHI FUJIO
Department of Internal Medicine, National Cardiovascular Center
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IKEDA MASAO
Department of Internal Medicine, National Cardiovascular Center
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Kojima Shunichi
Department Of Cardiovascular Medicine Hokkaido University School Of Medicine
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Tsuchiya Masayuki
Department Of Medicine National Cardiovascular Center
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Natsume Takashi
Department Of Cardiology Jichi Medical School
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Uda Masanobu
Department Of Internal Medicine National Cardiovascular Center Hospital
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Itoh Keiichi
Department Of Materials Science And Engineering Nagoya Institute Of Technology
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Tanaka Toshiyuki
Department Of Applied Chemistry Faculty Of Engineering University Of Toyama
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KIMURA Genjiro
Department of Medicine, National Cardiovascular Center Hospital
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TANAKA Toshiyuki
Department of Medicine, National Cardiovascular Center Hospital
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ASHIDA Hidenao
Department of Medicine, National Cardiovascular Center Hospital
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DEGUCHI Fujio
Department of Medicine, National Cardiovascular Center Hospital
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KOJIMA Shunichi
Department of Medicine, National Cardiovascular Center Hospital
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UDA Masanobu
Department of Medicine, National Cardiovascular Center Hospital
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IKEDA Masao
Department of Medicine, National Cardiovascular Center Hospital
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