CIRCADIAN RHYTHM OF BLOOD PRESSURE IN PRIMARY ALDOSTERONISM AND RENOVASCULAR HYPERTENSION : Analysis by the Cosinor Method
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概要
- 論文の詳細を見る
The circadian rhythm of blood pressure in 11 patients with primary aldosteronism (ALD) and 15 patients with unilateral renovascular hypertension (RVH) was analyzed using the cosinor method which fits a cosine function to a series of data. In ALD, both systolic (SP) and diastolic blood pressures (DP) increased in the late evening ; the amplitude and acrophase of the circadian rhythm for SP were 7.3 (5.3 to 9.3, mean and 95% confidence limits) mmHg and 20 : 47 (19:42 to 21:52) hours, respectively, and for DP 2.6 (1.3 to 3.9) mmHg and 21:34 (19:40 to 23:28) hours, respectively. After excision of an adrenal adenoma in 6 patients, the circadian rhythm of SP and DP was abolished. In RVH, the acrophase of the circadian rhythm of SP and DP differed by about 12 hours ; the amplitude and acrophase for SP were 5.7 (3.9 to 7.5) mmHg and 17:49 (16:35 to 19:02) hours, respectively, and for DP 1.5(0.2 to 2.7) mmHg and 6:08 (2:44 to 9:31) hours, respectively. After various surgical interventions in 8 patients, the circadian rhythm of SP persisted with little change in acrophase, while that of DP disappeared. The difference in circadian rhythm suggests a difference in mechanisms of blood pressure control in ALD and RVH.
- 社団法人日本循環器学会の論文
- 1983-07-20
著者
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Ashida Terunao
Department Of Medicine National Cardiovascular Center
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TANAKA Toshiyuki
Department of Urology, Osaka University Graduate School of Medicine
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NATSUME TAKASHI
Department of Internal Medicine, National Cardiovascular Center
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SHIBATA HAJIME
Department of Internal Medicine, National Cardiovascular Center
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IKEDA MASAO
Department of Internal Medicine, National Cardiovascular Center
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Ikeda Masao
Jichi Medical College
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Tsuchiya Masayuki
Department of Medicine, National Cardiovascular Center
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IKEDA MASAO
Cerebrovascular Division, Department of Internal Medicine, National Cardiovascular Center
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NOZAWA KEN-ICHI
Department of Medicine, National Cardiovascular Center
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KOJIMA SHUN-ICHI
Department of Medicine, National Cardiovascular Center
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TANAKA TOSHIYUKI
3rd Department oflnternal Medicine. Faculty ofMedicine. University of Tokyo
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Shibata Hajime
Department Of Internal Medicine National Cardiovascular Center
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Ikeda Masao
Cerebrovascular Division Department Of Internal Medicine National Cardiovascular Center
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Kojima Shunichi
The National Cardiovascular Center
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Kojima Shunichi
Division Of Hypertension And Nephrology National Cardiovascular Center
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Tsuchiya Masayuki
Department Of Medicine National Cardiovascular Center
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Ikeda Masao
Department Of Medicine National Cardiovascular Center
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Natsume Takashi
Department Of Internal Medicine National Cardiovascular Center
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Natsume Takashi
Department Of Cardiology Jichi Medical School
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Tanaka Toshiyuki
Department Of Endocrinology And Metabolism National Research Institute For Child Health And Developm
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Tanaka Toshiyuki
Department Of Medicine National Cardiovascular Center
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Natsume Takashi
Department Of Medicine National Cardiovascular Center
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Nozawa Ken-ichi
Department Of Medicine National Cardiovascular Center
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Ikeda Masao
The Third Deportment Of Internal Medicine Faculty Of Medicine University Of Tokyo
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Shibata Hajime
Department Of Applied Physics Faculty Of Engineering Tohoku University
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Ikeda Masao
The 3rd Dept. Of Intrn. Med. Faculty Of Med. Univ. Of Tokyo
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Ikeda Masao
Third Dept. Intern. Med. Fac. Med. Univ. Of Tokyo.
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Tanaka Toshiyuki
Department Of Applied Physics And Physico-informatics Keio University
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Tanaka Toshiyuki
Department Of Applied Chemistry Faculty Of Engineering University Of Toyama
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Ashida Terunao
Department of Medicine, National Cardiovascular Center
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