Developmental Course of Hypertension in the SHR-Substrains Susceptible to Hypertensive Cerebrovascular Lesions
スポンサーリンク
概要
- 論文の詳細を見る
The present study on the developmental course of hypertension in some substrains of SHR with marked differences in the incidence of cerebrovascular lesions clarified that rapidly developed and augmented hypertension was probably related to the higher incidence of cerebrovascular lesions. Accelerated development of severe hypertension in young stage seems to cause greater damage in relatively immature vascular wall and initiate the vicious sequence finally ensuing in cerebrovascular lesions. However, possible involvement of other factors than severe hypertension in the difference of vascular vulnerability in the substrain can not be eliminated and is still under investigation.
- International Heart Journal刊行会の論文
著者
-
Tomimoto Kazuhiko
Department Of Cardiology Shizuoka Central Prefectural Hospital Shizuoka
-
Ooshima Akira
Department Of Pathology Faculty Of Medicine Kyoto University
-
OOSHIMA Akira
Department of Pathology, Faculty of Medicine, Kyoto University
-
Yamori Yukio
Department of Life Science, Graduate School of Human and Environmental, Kyoto University
-
Hazama Fumitada
Deparment of Pathology, Shiga University of Medical Science, School of Medicine
-
Okamoto Kozo
Department of Clinical Functional Physiology, Toho University
関連論文
- Clinical and Histopathological Studies in Children With Supraventricular Tachycardia
- HISTOPATHOLOGICAL STUDY ON KAWASAKI DISEASE WITH SPECIAL REFERENCE TO THE RELATION BETWEEN THE MYOCARDIAL SEQUELAE AND REGIONAL WALL MOTION ABNORMALITIES OF THE LEFT VENTRICLE
- -0950-CLINICAL AND PATHOLOGIC ANALYSIS OF MYOCARDIAL DAMAGES FOLLOWING KAWASAKI DISEASE EMPLOYING ENDOMYOCARDIAL BIOPSY : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -49-CLINICAL INVESTIGATIONS ON THE INFANTS AND CHILDREN WITH IDIOPATHIC MULTIFORM VENTRICULAR PREMATURE CONTRACTIONS : Arrhythmias : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Distribution of Twenty-Four Hour Urinary Taurine Excretion and Association with Ischemic Heat Disease Mortality in 24 Populations of 16 Countries : Results from the WHO-CARDIAC Study
- EFFECTS OF E-1020, A NEW CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE INHIBITOR, ON CYCLIC AMP AND CYTOSOLIC FREE CALCIUIM OF CULTURED VASCULAR SMOOTH MUSCLE CELLS : The 53th Annual Scientific Session of the Japanese Circulation Society
- STUDY OF THE PATHOGENESIS OF CARDIAC HYPERTROPHY : Biochemical Differences of Cultured Heart Cells from Normotensive and Spontaneously Hypertensive Rats
- EFFECTS OF E-1020, A NEW cAMP-SPECIFIC PHOSPHODIESTERASE INHIBITOR, ON PROTEIN METABOLISM OF HEART AND cAMP OR CYTOSOLIC FREE Ca^ OF VASCULAR SMOOTH MUSCLE CELLS : Cardiovascular Drugs : 53 Annual Scientific Meeting, Japanese Circulation Society
- -P210- THE METABOLIC DIFFERENCES OF CULTURED HEART CELLS IN SHR & WKY
- Cardiovascular Risk Factors Emerging in Chinese Populations Undergoing Urbanization
- Augmentation of Spontaneous Hypertension by Chronic Stress in Rats
- Adrenal Catecholamine Content in the Spontaneously Hypertensive Rats
- Enzyme-histochemical Studies on the Brain Stem of Spontaneously Hypertensive Rats
- Enzyme Histochemical Studies on the Hypothalamus of Spontaneously Hypertensive Rates : With Special Reference to That of Rats Subjected to Various Endocrinc Interferences
- Pharmacodynamic Studies on the Cardiovascular System of Spontaneously Hypertensive Rats
- A sporadic case of Ehlers-Danlos syndrome type IV : Diagnosed by a morphometric study of collagen content
- PLASMA RENIN AND HYPERTENSIVE VASCULAR COMPLICATIONS : AN OBSERVATION IN THE STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RAT
- Hypertensive Vascular Lesions and Renin or Lysosomal Enzymes in Rats
- 4) HISTOPATHOLOGICAL INVESTIGATION OF VARIOUS ORGANS IN MYOCARDIAL ISCHEMIC RATS (MIR)
- 1)NOREPINEPHRINE-INDUCED HYPERTROPHY OF CULTURED MYOCYTES : THE 7th CONFERENCE ON CARDIOMYOPATHY
- EFFECT OF SODIUM-LOAD ON ATRIAL AND PLASMA ANP LEVELS OF SPONTANEOUSLY HYPERTENSIVE RAT : Atrial Natriuretic Polypeptide (I) : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Extract of Wine Phenolics Improves Aortic Biomechanical Properties in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP)
- FAMILIAL CONGESTIVE CARDIOMYOPATHY WITH POSITIVE RHEUMATOID FACTOR : REPORT OF ONE FAMILY.
- -170-Na^+-H^+ EXCHANGE ACTIVITY AND CYTOPLASMIC pH IN CULTURED VASCULAR SMOOTH MUSCLE CELLS FROM STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS : Cardiac Metabolism, Cardiac Biochemistry : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC M
- CHANGES IN HEMODYNAMICS WITH ADVANCING AGE IN CONSCIOUS SPONTANEOUSLY HYPERTENSIVE RATS
- Cellular Fibronectin, but not Collagens, Disappears in the Central Posterior Capsules During Healing After Lens Extraction and IOL Implantation in Rabbits
- Alterations in Ultrastructure and c-met Expression in a Case of Ocular Epithelial Dysplasia Following Topical Mitomycin C Treatment
- Pathological Findings in Lens Capsule and Silicone Intraocular Lens Extracted From Eye With Chronic Infectious Endophthalmitis
- Immunohistochemical Identification of Proteoglycan Types in Fibrotic Human Capsules With Intraocular Lens Implants
- GLUCOSE TOLERANCE IN SPONTANEOUSLY HYPERTENSIVE RATS
- Morphological Analysis of the Pathogenesis of Hypertensive Cerebrovascular Lesions: Role of Monocytes and Platelets in Intracerebral Vessel Occlusions : THE 17th CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
- STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS AS A MODEL FOR TOXEMIA OF PREGNANCY AND AGGRAVATING AND PREVENTIVE EFFECTS OF MATERNAL MODIFICATIONS DURING PREGNANCY ON OFFSPRING'S GROWTH : The 53th Annual Scientific Session of the Japanese Circulation Socie
- Experimental and Clinical Studies on the Relationship between Genetic Hypertension and Glucose Metabolism
- Further Vectorcardiographical and Pathotopographical Studies on the Heart of Spontaneously Hypertensive Rats (SHR)
- VECTORCARDIOGRAPHIC STUDY ON LEFT VENTRICULAR HYPERTROPHY IN SPONTANEOUSLY HYPERTENSIVE RATS
- COLLAGEN IN DILATED CARDIOMYOPATHY : Scanning Electron Microscopic and Immunohistochemical Observations
- -1045-COLLAGEN REMODELING IN THE HUMAN HYPERTENSIVE HYPERTROPHIED HEARTS : IMMUNOHISTOCHEMICAL AND SCANNING ELECTRON MICRASCOPIC OBSERVATIONS : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -0032-MORPHOLOGICAL CHARACTERISTICS OF COLLAGENS IN DILATED CARDIOMYOPATHY : SCANNING ELECTRON MICROSCOPIC AND IMMUNOHISTOCHEMICAL OBSERVATIONS
- Molecular Cloning and Sequencing of a cDNA Encoding Alanine-Glyoxylate Aminotransferase 2 from Rat Kidney
- Pathogenesis of Acute Arterial Fat Deposition in Spontaneously Hypertensive Rats
- Importance of Genetic Factors in Stroke--An Evidence Obtained by Selective Breeding of Stroke-prone and -resistant SHR (3 Conference of Pathogenesis of Hypertension)
- PARABIOTIC EFFECT ON BLOOD PRESSURE IN SPONTANEOUSLY HYPERTENSIVE RATS
- CHEMICAL ANALYSIS OF VASCULAR COLLAGEN IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS
- Pathogenesis of Spontaneous Hypertension as a Model for Essential Hypertension : SYMPOSIUM ON PATHOGENESIS OF ESSENTIAL HYPERTENSION
- Experimental Studies on the Pathogenesis and Prophylaxis of Stroke in Stroke-prone Spontaneously Hypertensive Rats(SHR) : (1) Quantitative Estimation of Cerebrovascular Permeability
- VASCULAR LESIONS IN THE VARIOUS SUBSTRAINS OF SPONTANEOUSLY HYPERTENSIVE RATS AND THE EFFECTS OF CHRONIC SALT INGESTION
- DEVELOPMENT OF SUBSTRAINS IN SPONTANEOUSLY HYPERTENSIVE RATS: GENEALOGY, ISOZYMES AND EFFECT OF HYPERCHOLESTEROLEMIC DIET
- PHYSIOLOGICAL IMPLICATION OF THE L-ARGININE-NITRIC OXIDE PATHWAY IN CIRCULATION
- EFFECTS OF HIGH OR LOW SODIUM INTAKE IN SPONTANEOUSLY HYPERTENSIVE RATS
- Effect of Ascorbic Acid on the Development of Stroke in Stroke-Prone SHR
- Prophylactic Trials for Stroke in Stroke-Prone SHR : Effect of Sex Hormones
- Experimental Studies on Sex Difference in Stroke-Prone SHR (SHRSP) : Hypoxic Vulnerability and Aortic Brittleness
- Fas-mediated upregulation of vascular endothelial growth factor and monocyte chemoattractant protein-1 expression in cultured dermal fibroblasts : Role in the inflammatory response
- Genetic Analysis of Blood Pressure in Spontaneously Hypertensive Rats
- Deviation of Central Norepinephrine Metabolism in Hypertensive Rats
- CARDIOVASCULAR LESIONS IN THE SELECTIVELY-BRED GROUP OF SPONTANEOUSLY HYPERTENSIVE RATS WITH SEVERE HYPERTENSION
- Genetic Factors Involved in Spontaneous Hypertension in Rats An Analysis of F_2 Segregate Generation
- Participation of Neural Factor in the Pathogenesis of Hypertension in the Spontaneously Hypertensive Rat
- Renal Function, Plasma Renin, and Spontaneous Diuresis in an Advanced Stage of Hypertension in Rats
- Corneal Epithelial Basement Membrane After Experimental Anterior Stromal Puncture in Guinea Pigs : Immunohistochemical Study
- COLLAGEN TYPES IN HEALING ALKALI-BURNED CORNEAL STROMA IN RABBITS
- Detection of Biomembrane Abnormalities of Erythrocytes from Stroke-Prone SHR (SHRSP) before the Development of Hypertension by the Method of Tetraphenyl-Phosphonium Electrode and Its Preliminary Application to Men
- INCREASED LYSYL OXIDASE ACTIVITY IN BLOOD VESSELS OF HYPERTENSIVE RATS AND EFFECT OF β-AMINOPROPIONITRILE ON ARTERIOSCLEROSIS
- ENZYMOLOGICAL STUDIES ON ARTERIES IN SPONTANEOUSLY HYPERTENSIVE RATS
- Human Type VI Collagen : Purification from Human Subcutaneous Fat Tissue and an Immunohistochemical Study of Morphea and Systemic Sclerosis
- LOCALIZATION OF PROLYL HYDROXYLASE BY THE IMMUNOPEROXIDASE METHOD IN CARDIOVASCULAR TISSUES OF HYPERTENSIVE RATS
- EPIDEMIOLOGICAL ANALYSIS ON THE MECHANISM OF CIGARETTE SMOKING AS A RISK FACTOR IN CARDIOVASCULAR DISEASES
- Vascular Changes in the Various Substrains of Spontaneously Hypertensive Rats, Untreated and Treated with Sodium Chloride in Diet
- Metabolism of Adrenal Corticosteroids in Spontaneously Hypertensive Rats
- The Spontaneously Hypertensive Rat (8) : Proceedings of VIII Annual Scientific Meeting of the Council for the Spontaneously Hypertensive Rat October 8, 1972, Nagasaki
- Effect of α-rat Atrial Natriuretic Polypeptide on Blood Pressure in Rats Bilateral Renal Vessels Ligated
- Relation between Changes in Optic Fundi and the Development of Cardiovascular Diseases:a Preliminary Report (2)
- Genetic Analysis of the rat Na-K-2Cl Cotransporter (NKCC2) Gene in SHRSP/Izm:Positional Candidate Approach
- EFFECT OF SMOKING ON CHOLESTEROL METABOLISM IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
- Atrial natriuretic polypeptide (ANP) in spontanenously hypertensive rats:Evidence for the increased secretion of ANP from the heart
- Cellular Mechanisms of Cardiovascular Hypertrophy in Spontaneously Hypertensive Rats (SHR) and Their Modification
- Effect of Radiation on the Heart in SHRSP:stroke-prone spontaneously hypertensive rats
- Effect of α-human Atrial Natriuretic Polypeptide (α-hANP) on Canine Renal Na+-K+ ATPase Activity
- Effect on Na+, K+ ATPase Activity of Erythrocytes after Acute and Chronic Salt Loading in Normotensive WKY Rats
- INCREASED URINARY CATECHOLAMINE EXCRETION IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR) UNDER COLD EXPOSURE
- Prophylactic Trials for Stroke in Stroke-Prone SHR (7):Effect of Various Lipid-Rich Diets on Hypertension, Lipoprotein-Profiles and Fatty Metamorphosis of the Liver
- Effects of DOCA and Salt Overloading on the Content of α-Rat Atrial Natriuretic Polypeptide-like Immunoreactivity in Rat Atrium
- Radioimmunoassay for Atrial Natriuretic Polypeptide
- Relaxant effects of sauvagine on vascular strips of SHR and WKY with special reference on endogenously synthesized prostaglandins
- Rearing of SHRSP at Different Environmental Temperatures-Effect of High-Fat and High-Protein Diets
- Physical Characteristics of the Aortas in Old Stroke-prone Spontaneously Hypertensive Rats
- Relationship between Intracellular Free Ca2+, Mg2+ and Blood Pressure in Prehypertensive and Hypertensive SHRSP and age-mutched WKY
- Analysis on the Vectorcardiographical Pattern of SHR at Various Ages
- Brain metabolism under bilateral arteries ligatation of stroke-prone spontaneously hypertensive rats studied with 31P-NMR
- Atrial Natriuretic Polypeptides in SHR and SHR Stroke-Prone
- Collagen Biosynthetic Activity of Cultured Medial Smooth Muscle Cells Devided from the Thoracic Aortas of Stroke-Prone Spontaneously Hypertensive Rats
- The Effect of Hyperbaric Oxygenation on Vascular Protein of Stroke-Prone and Resistant SHR
- Synaptosomal Membrane Characteristics in Stroke-prone SHR (SHRSP), Stroke-resistant SHR (SHRSR) and Wistar-Kyoto Rats (WKY)
- Atrial Natriuretic Polypeptides in Rat Heart and Plasma
- Effect of Long-term Salt-loading on Heart Weight in Rats
- Characteristics of Cultured Vascular Smooth Muscle Cells from SHR
- Biochemical Aspect of Salt Induced Left Ventricular Hypertrophy in Rats
- Lipid accumulation in cultured vascular smooth muscle cells (VSMC) from the aorta of strokeprone SHR (SHRSP) under hypoxic condition
- Structural Vascular Alteration in Relation to Cardiac Hypertrophy in SHR
- Developmental Course of Hypertension in the SHR-Substrains Susceptible to Hypertensive Cerebrovascular Lesions