CHEMICAL ANALYSIS OF VASCULAR COLLAGEN IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS
スポンサーリンク
概要
- 論文の詳細を見る
Chemical characteristics of vascular collagen were studied in stroke-prone spontaneously hypertensive rats (SHRSP) which developed cerebrovascular lesions spontaneously in over 90% of the population. Aminoacid analysis of arterial collagen among SHRSP showed no remarkable difference from stroke-resistant SHR (SHRSR) and normotensive Wistar-Kyoto rats (WK). The uronic acid content of the aorta, which elevated with aging, was increased in SHRSR and especially in SHRSP. The hexose content of collagen was also increased in SHRSP characteristically with a concomitant increase in the ratio of the disaccharide unit (glucosyl-galactosyl-hydroxylysine) to the monosaccharide (galactosyl-hydroxylysine). The relative increase in β and γ components was also noted in SHRSP. These structural changes of vascular collagen especially noted in SHRSP may be related to the fragility of arterial wall or to the stroke-proneness.
- 社団法人日本循環器学会の論文
- 1979-11-20
著者
-
Yamori Yukio
Department Of Pathology Faculty Of Medicine Kyoto University
-
Yamori Yukio
Department Of Pathology Shimane Medical University Japan Stroke Prevention Center
-
OHTA KIYOE
Department of Pathology, Faculty of Medicine, Kyoto University Japan Stroke Prevention Center
-
Ohta Kiyoe
Department Of Pathology Faculty Of Medicine Kyoto University Japan Stroke Prevention Center
-
Ohta Kiyoe
Department of Neurosurgeruy, Faculty of Medicine, Kyoto University
-
Yamori Yukio
Department of Life Science, Graduate School of Human and Environmental, Kyoto University
関連論文
- Distribution of Twenty-Four Hour Urinary Taurine Excretion and Association with Ischemic Heat Disease Mortality in 24 Populations of 16 Countries : Results from the WHO-CARDIAC Study
- EFFECTS OF E-1020, A NEW CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE INHIBITOR, ON CYCLIC AMP AND CYTOSOLIC FREE CALCIUIM OF CULTURED VASCULAR SMOOTH MUSCLE CELLS : The 53th Annual Scientific Session of the Japanese Circulation Society
- STUDY OF THE PATHOGENESIS OF CARDIAC HYPERTROPHY : Biochemical Differences of Cultured Heart Cells from Normotensive and Spontaneously Hypertensive Rats
- EFFECTS OF E-1020, A NEW cAMP-SPECIFIC PHOSPHODIESTERASE INHIBITOR, ON PROTEIN METABOLISM OF HEART AND cAMP OR CYTOSOLIC FREE Ca^ OF VASCULAR SMOOTH MUSCLE CELLS : Cardiovascular Drugs : 53 Annual Scientific Meeting, Japanese Circulation Society
- -P210- THE METABOLIC DIFFERENCES OF CULTURED HEART CELLS IN SHR & WKY
- Cardiovascular Risk Factors Emerging in Chinese Populations Undergoing Urbanization
- Augmentation of Spontaneous Hypertension by Chronic Stress in Rats
- Adrenal Catecholamine Content in the Spontaneously Hypertensive Rats
- Enzyme-histochemical Studies on the Brain Stem of Spontaneously Hypertensive Rats
- Studies on the Autonomic Nervous System of Spontaneously Hypertensive Rats
- Enzyme Histochemical Studies on the Hypothalamus of Spontaneously Hypertensive Rates : With Special Reference to That of Rats Subjected to Various Endocrinc Interferences
- Pharmacodynamic Studies on the Cardiovascular System of Spontaneously Hypertensive Rats
- Further Observations of the Development of a Strain of Spontaneously Hypertensive Rats
- Experimental Hypertension and Hypotension Induced by Hypothalamic Destruction in the Rat
- Plasma Renin and Vascula Complications in Substrains of the Spontaneously Hypertensive Rat, with a Reference to Water and Electrolyte Balance
- PLASMA RENIN AND HYPERTENSIVE VASCULAR COMPLICATIONS : AN OBSERVATION IN THE STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RAT
- Hypertensive Vascular Lesions and Renin or Lysosomal Enzymes in Rats
- 4) HISTOPATHOLOGICAL INVESTIGATION OF VARIOUS ORGANS IN MYOCARDIAL ISCHEMIC RATS (MIR)
- 1)NOREPINEPHRINE-INDUCED HYPERTROPHY OF CULTURED MYOCYTES : THE 7th CONFERENCE ON CARDIOMYOPATHY
- EFFECT OF SODIUM-LOAD ON ATRIAL AND PLASMA ANP LEVELS OF SPONTANEOUSLY HYPERTENSIVE RAT : Atrial Natriuretic Polypeptide (I) : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Extract of Wine Phenolics Improves Aortic Biomechanical Properties in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP)
- -170-Na^+-H^+ EXCHANGE ACTIVITY AND CYTOPLASMIC pH IN CULTURED VASCULAR SMOOTH MUSCLE CELLS FROM STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS : Cardiac Metabolism, Cardiac Biochemistry : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC M
- CHANGES IN HEMODYNAMICS WITH ADVANCING AGE IN CONSCIOUS SPONTANEOUSLY HYPERTENSIVE RATS
- RENAL VASCULAR LESIONS AND RENIN ACTIVITIES IN RATS TREATED WITH DOCA PLUS HIGH SALT OR WITH HIGH SALT : (Part III)
- GLUCOSE TOLERANCE IN SPONTANEOUSLY HYPERTENSIVE RATS
- Morphological Analysis of the Pathogenesis of Hypertensive Cerebrovascular Lesions: Role of Monocytes and Platelets in Intracerebral Vessel Occlusions : THE 17th CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
- STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS AS A MODEL FOR TOXEMIA OF PREGNANCY AND AGGRAVATING AND PREVENTIVE EFFECTS OF MATERNAL MODIFICATIONS DURING PREGNANCY ON OFFSPRING'S GROWTH : The 53th Annual Scientific Session of the Japanese Circulation Socie
- Experimental and Clinical Studies on the Relationship between Genetic Hypertension and Glucose Metabolism
- Further Vectorcardiographical and Pathotopographical Studies on the Heart of Spontaneously Hypertensive Rats (SHR)
- VECTORCARDIOGRAPHIC STUDY ON LEFT VENTRICULAR HYPERTROPHY IN SPONTANEOUSLY HYPERTENSIVE RATS
- Pathogenesis of Acute Arterial Fat Deposition in Spontaneously Hypertensive Rats
- Importance of Genetic Factors in Stroke--An Evidence Obtained by Selective Breeding of Stroke-prone and -resistant SHR (3 Conference of Pathogenesis of Hypertension)
- Baroreceptor Function Revealed by Acute Sinoaortic Denervation in Spontaneously Hypertensive Rats
- PARABIOTIC EFFECT ON BLOOD PRESSURE IN SPONTANEOUSLY HYPERTENSIVE RATS
- CHEMICAL ANALYSIS OF VASCULAR COLLAGEN IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS
- Hypothalamic Tonic Regulation of Blood Pressure in Spontaneously Hypertensive Rats
- Experimental Studies on the Pathogenesis and Prophylaxis of Stroke in Stroke-prone Spontaneously Hypertensive Rats (SHR) : (2) Prophylactic Effect of Moderate Control of Blood Pressure on Stroke
- Vascular Protein Metabolism in the Pathogenesis of Hypertension
- Pathogenesis of Spontaneous Hypertension as a Model for Essential Hypertension : SYMPOSIUM ON PATHOGENESIS OF ESSENTIAL HYPERTENSION
- Experimental Studies on the Pathogenesis and Prophylaxis of Stroke in Stroke-prone Spontaneously Hypertensive Rats(SHR) : (1) Quantitative Estimation of Cerebrovascular Permeability
- DEVELOPMENT OF SUBSTRAINS IN SPONTANEOUSLY HYPERTENSIVE RATS: GENEALOGY, ISOZYMES AND EFFECT OF HYPERCHOLESTEROLEMIC DIET
- PHYSIOLOGICAL IMPLICATION OF THE L-ARGININE-NITRIC OXIDE PATHWAY IN CIRCULATION
- EFFECTS OF HIGH OR LOW SODIUM INTAKE IN SPONTANEOUSLY HYPERTENSIVE RATS
- Prophylactic Trials for Stroke in Stroke-Prone SHR : Effect of Sex Hormones
- Genetic Analysis of Blood Pressure in Spontaneously Hypertensive Rats
- Deviation of Central Norepinephrine Metabolism in Hypertensive Rats
- CARDIOVASCULAR LESIONS IN THE SELECTIVELY-BRED GROUP OF SPONTANEOUSLY HYPERTENSIVE RATS WITH SEVERE HYPERTENSION
- Genetic Factors Involved in Spontaneous Hypertension in Rats An Analysis of F_2 Segregate Generation
- Participation of Neural Factor in the Pathogenesis of Hypertension in the Spontaneously Hypertensive Rat
- Renal Function, Plasma Renin, and Spontaneous Diuresis in an Advanced Stage of Hypertension in Rats
- Detection of Biomembrane Abnormalities of Erythrocytes from Stroke-Prone SHR (SHRSP) before the Development of Hypertension by the Method of Tetraphenyl-Phosphonium Electrode and Its Preliminary Application to Men
- EPIDEMIOLOGICAL ANALYSIS ON THE MECHANISM OF CIGARETTE SMOKING AS A RISK FACTOR IN CARDIOVASCULAR DISEASES
- Metabolism of Adrenal Corticosteroids in Spontaneously Hypertensive Rats
- The Spontaneously Hypertensive Rat (8) : Proceedings of VIII Annual Scientific Meeting of the Council for the Spontaneously Hypertensive Rat October 8, 1972, Nagasaki
- Effect of α-rat Atrial Natriuretic Polypeptide on Blood Pressure in Rats Bilateral Renal Vessels Ligated
- Relationship between Arterial Lesions of the Retina and the Brain in Stroke-prone SHR (SHRSP)
- Relation between Changes in Optic Fundi and the Development of Cardiovascular Diseases:a Preliminary Report (1)
- Relation between Changes in Optic Fundi and the Development of Cardiovascular Diseases:a Preliminary Report (2)
- Genetic Analysis of the rat Na-K-2Cl Cotransporter (NKCC2) Gene in SHRSP/Izm:Positional Candidate Approach
- EFFECT OF SMOKING ON CHOLESTEROL METABOLISM IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
- Atrial natriuretic polypeptide (ANP) in spontanenously hypertensive rats:Evidence for the increased secretion of ANP from the heart
- Cellular Mechanisms of Cardiovascular Hypertrophy in Spontaneously Hypertensive Rats (SHR) and Their Modification
- Effect of Radiation on the Heart in SHRSP:stroke-prone spontaneously hypertensive rats
- Effect of α-human Atrial Natriuretic Polypeptide (α-hANP) on Canine Renal Na+-K+ ATPase Activity
- Effect on Na+, K+ ATPase Activity of Erythrocytes after Acute and Chronic Salt Loading in Normotensive WKY Rats
- INCREASED URINARY CATECHOLAMINE EXCRETION IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR) UNDER COLD EXPOSURE
- Prophylactic Trials for Stroke in Stroke-Prone SHR (7):Effect of Various Lipid-Rich Diets on Hypertension, Lipoprotein-Profiles and Fatty Metamorphosis of the Liver
- Effects of DOCA and Salt Overloading on the Content of α-Rat Atrial Natriuretic Polypeptide-like Immunoreactivity in Rat Atrium
- Radioimmunoassay for Atrial Natriuretic Polypeptide
- Relaxant effects of sauvagine on vascular strips of SHR and WKY with special reference on endogenously synthesized prostaglandins
- Effects of urotensin I and sauvagine on vascular strips of SHR and WKY
- Rearing of SHRSP at Different Environmental Temperatures-Effect of High-Fat and High-Protein Diets
- Physical Characteristics of the Aortas in Old Stroke-prone Spontaneously Hypertensive Rats
- Effect of Salt Loading on Fatty Acid Composition in Various Organs of Stroke-Prone SHR (SHRSP)
- Relationship between Intracellular Free Ca2+, Mg2+ and Blood Pressure in Prehypertensive and Hypertensive SHRSP and age-mutched WKY
- Analysis on the Vectorcardiographical Pattern of SHR at Various Ages
- Brain metabolism under bilateral arteries ligatation of stroke-prone spontaneously hypertensive rats studied with 31P-NMR
- Atrial Natriuretic Polypeptides in SHR and SHR Stroke-Prone
- Collagen Biosynthetic Activity of Cultured Medial Smooth Muscle Cells Devided from the Thoracic Aortas of Stroke-Prone Spontaneously Hypertensive Rats
- The Effect of Hyperbaric Oxygenation on Vascular Protein of Stroke-Prone and Resistant SHR
- Hemodynamic Characteristics of young and adult SHR measured in awake States
- Synaptosomal Membrane Characteristics in Stroke-prone SHR (SHRSP), Stroke-resistant SHR (SHRSR) and Wistar-Kyoto Rats (WKY)
- Atrial Natriuretic Polypeptides in Rat Heart and Plasma
- Effect of Long-term Salt-loading on Heart Weight in Rats
- Characteristics of Cultured Vascular Smooth Muscle Cells from SHR
- Biochemical Aspect of Salt Induced Left Ventricular Hypertrophy in Rats
- Lipid accumulation in cultured vascular smooth muscle cells (VSMC) from the aorta of strokeprone SHR (SHRSP) under hypoxic condition
- Effect of Sodium or Potassium Loading on Reactive Hypercholesterolemia in Rats
- Cardiovascular DNA and RNA Contents during the Development of Cardiac Enlargement in Rats
- Effects of Maternal Administration of KCl and Hydralazine on Their Offspring's Growth
- Effect of Various Fatty Acids on Proliferation of Cultured Smooth Muscle Cells (SMC) from the Aorta of Stroke-Prone SHR (SHRSP)
- Comparison of Na+-H+ Exchange Activity in Cultured Vascular Smooth Muscle Cells between Stroke-Prone SHR and WKY
- Studies on Stroke in Stroke-Prone Spontaneously Hypertensive Rat (SHRSP):(II) Cerebrovascular Fat Deposition and Cerebrovascular Permeability
- Studies on Stroke in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP):(I) Local Factor Analysis on Stroke
- Experimental Studies on Atherogenesis:(I) Acute Arterial Fat Deposition in Various Hypertensive Rats
- Analysis of Environmental Factors on the Development of Stroke in Strokeprone SHR:Influence of Types of Cages with or without Bedding
- The Study of Mevalonic Acid Metabolites in Spontanously Hypertensive and Normotensive Rat
- Analysis of Right Ventricular Hypertrophy in Spontaneously Hypertensive Rats:Relationship between Pressure Load and Hypertrophy
- Quantitative Observations of Fine Structure of Myocardial Plasma Membrane in Rat Ventricle
- Essential Difference in Pathogenesis of Arteriosclerosis and Atherosclerosis in the Retinal Arteries and Other Arteries