ENZYMOLOGICAL STUDIES ON ARTERIES IN SPONTANEOUSLY HYPERTENSIVE RATS
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概要
- 論文の詳細を見る
Alkaline phosphatase activity of mesenteric arteries was markedly increased in spontaneously hypertensive rats (SHR) compared to normotensive rats (NR). The aorta showed almost the same tendency, but was not so remarkable as mesenteric arteries. Furthermore, a positive correlation between alkaline phosphatase activity of mesenteric arteries and the blood pressure level was observed in the F_2 segregate generation. Slight but significantly high enzymatic activities were also detected in acid phosphatase of the aorta, in glucose-6-phosphate dehydrogenase of the aorta and in lactic dehydrogenase of the heart in SHR. In addition to these findings, differences in the electrophoretic pattern of esterase isozymes of mesenteric arteries and the aorta between SHR and NR were detected. These enzymological abnormalities in the cardiovascular system, especially mesenteric arteries, might have some relationship to the development and/or the maintenance of genetic hypertension in SHR.
- 社団法人日本循環器学会の論文
- 1973-08-20
著者
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Ooshima Akira
Department Of Pathology Faculty Of Medicine Kyoto University
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OOSHIMA Akira
Department of Pathology, Faculty of Medicine, Kyoto University
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