Delayed-Type Hypersensitivity in Sheep Induced by Synthetic Peptides of Bovine Leukemia Virus Encapsulated in Mannan-Coated Liposome
スポンサーリンク
概要
- 論文の詳細を見る
Four sheep were immunized with synthesized peptides, derived from bovine leukemia virus (BLV) envelope glycoprotein, encapsulated in mannan coated liposomes as adjuvant. On the seventh day after the immunization, the sheep were intradermally challenged with BLV antigen, or synthesized peptides. The areas challenged with antigen were increased skin thickness and biopsied sequentially for immunohistological examinations. Strong delayed-type hypersensitivity was induced in sheep immunized and challenged with peptides encapsulated in mannan-coated liposomes. The major phenotype of the infiltrating lymphocytes was CD5+. The ratio of CD4+ to CD8+ cells was about 1:1.
- 公益社団法人 日本獣医学会の論文
著者
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ONUMA Misao
Department of Epizootiology, Faculty of Veterinary Medicine, Hokkaido University
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Chen Sau
Department Of Veterinary Pathology Faculty Of Agriculture Iwate University
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Okada Kosuke
Department Of Comparative Pathology Faculty Of Veterinary Medicine Hokkaido University
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Onuma Misao
Department Of Disease Control Graduate School Of Veterinary Medicine Hokkaido University
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Kabeya Hidenori
Department Of Disease Control Graduate School Of Veterinary Medicine Hokkaido University
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GORYO Masanobu
Department of Applied Veterinary Science, United Graduate School of Veterinary Science, Gifu University
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IKEDA Manabu
Department of Veterinary Pathology, Faculty of Agriculture, Iwate University
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Ikeda Manabu
Department of Applied Chemistry, Faculty of Engineering, Yokohama National University
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YIN Shanai
Department of Veterinary Pathology, Faculty of Agriculture, Iwate University
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OHISHI Kazue
Department of Veterinary Pathology, Faculty of Agriculture, Iwate University
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CHEN Sau
Department of Veterinary Pathology, Faculty of Agriculture, Iwate University
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SONODA Kai
Department of Veterinary Pathology, Faculty of Agriculture, Iwate University
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KOYAMA Masato
Department of Veterinary Pathology, Faculty of Agriculture, Iwate University
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