Comparative Susceptibility of Some Avian and Mammalian Lymphoblastoid Cell Lines to Chicken Anemia Virus
スポンサーリンク
概要
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Although MSB1 is the most-commonly used lymphoblastoid cell line for isolation of chicken anemia virus (CAV), some researchers reported a few biological drawbacks. None of them could be supported in this study. Another four avian (HP1, HP2, BK3 and CU10) and two mammalian (BTL-26 and KO-1) cell lines were investigated for susceptibility to TK-5803 and AH-9409 strains. Both strains caused CPE on BK3 like MSB1. The mean number of positive cells to each strain in MSB1 and BK3 were not significantly different. The majority of HP2, CU10 and HP1 cells showed no CPE. The virus titers of both strains were higher in MSB1 and BK3 (106.5–7.5 TCID50/ 0.1 ml) than in HP2, CU10 and HP1 (103.5–4.5 TCID50/ 0.1 ml). BTL-26 and KO-1 were resistant to CAV. BK3 could be used for isolation of CAV.
著者
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Okada Kosuke
Department Of Comparative Pathology Faculty Of Veterinary Medicine Hokkaido University
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Goryo Masanobu
Department Of Comparative Pathology Faculty Of Veterinary Medicine Hokkaido University
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Sasaki Jun
Department Of Internal Medicine Fukuoka University School Of Medicine
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HARIDY Mohie
Department of Pathogenetic Veterinary Science, The United Graduate School of Veterinary Science, Gif
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Sasaki Jun
Department Of Cardiovascular Surgery Sapporo Chuo Hospital
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Sasaki Jun
Department Of Applied Biological Science Tokyo University Of Agriculture And Technology
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GORYO Masanobu
Department of Applied Veterinary Science, United Graduate School of Veterinary Science, Gifu University
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GORYO Masanobu
Department of Pathogenetic Veterinary Science, The United Graduate School of Veterinary Science, Gifu University
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