Purification and Characterization of a Fibrinolytic Protease from a Culture Supernatant of Flammulina velutipes Mycelia
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概要
- 論文の詳細を見る
We compared the dietary effects of dihomo-γ-linolenic acid (DGLA) contained in the DGLA oil produced by a fungus with γ-linolenic acid (GLA) on the fatty acid composition. Wistar rats were fed with three kinds of oil for two weeks as follows: (i) control group: corn oil; (ii) GLA group: borage oil; (iii) DGLA group: DGLA oil/safflower oil = 55:45. The DGLA concentrations in the liver, serum, and brain of the DGLA group were higher than those of the GLA oil group. We also examined the dose effect of DGLA. The DGLA levels in the liver, serum, and brain significantly increased with increasing dosage of DGLA in the diet. DGLA administration significantly increased the ratio of PGE1/PGE2 in the rat plasma. The mechanism for GLA administration to improve atopic eczema is thought to involve an increase in the concentration of DGLA metabolized from GLA, so these results suggest that the dietary effect of DGLA would be more dominant than GLA.
- 社団法人 日本農芸化学会の論文
- 2007-09-23
著者
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Sapkota Kumar
Department of Biotechnology, Chosun University
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Park Se-Eun
Department of Biotechnology, Chosun University
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Kim Ji-Eun
Department of Biotechnology, Chosun University
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KIM Sung-Jun
Department of Biotechnology, Chosun University
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KIM Jae-Sung
Department of Radiation Oncology, Seoul National University College of Medicine
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UMEDA-SAWADA Rumi
Department of Food Science and Nutrition, Ochanomizu University
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Kim Ji-eun
Department Of Anatomy College Of Medicine Hallym University
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Ushiyama Ikuko
Department Of Nutrition And Food Science Ochanomizu University
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Ono Yoshiko
Institute For Health Care Science Suntory Ltd.
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Ushiyama Ikuko
Department Of Legal Medicine Shiga University Of Medical Science
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Morimitsu Yasujiro
Department Of Nutrition And Food Science Ochanomizu University
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LI Mei-Hong
Department of Biotechnology and BK21 Research Team for Protein Activity Control Chosun University
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CHOI Bong-Suk
Department of Biotechnology and BK21 Research Team for Protein Activity Control Chosun University
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YOON Yeon-Hee
Biotechnology Industrialization Center, Dongshin University
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LEE Jin-Cheol
Biotechnology Industrialization Center, Dongshin University
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LEE Hyun-Hwa
Department of Biology, Chosun University
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KIM Chun-Sung
Department of Pharmacology, University of Minnesota
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Lee Jin-cheol
Biotechnology Industrialization Center Dongshin University
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Yoon Yeon-hee
Biotechnology Industrialization Center Dongshin University
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Kim Jae-sung
Department Of Biotechnology And Bk21 Research Team For Protein Activity Control Chosun University
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Kim Chun-sung
Department Of Pharmacology University Of Minnesota
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Fujiwara Yoko
Department Of Food Science And Nutrition Ochanomizu University
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Kim Sung-jun
Department Of Biotechnology And Bk21 Research Team For Protein Activity Control Chosun University
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Park Se-eun
Department Of Biotechnology And Bk21 Research Team For Protein Activity Control Chosun University
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Lee Hyun-hwa
Department Of Biology Chosun University
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Sapkota Kumar
Department Of Biotechnology And Bk21 Research Team For Protein Activity Control Chosun University
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Kim Sung-jun
Department Of Alternative Medicine Gwangju University
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Fujiwara Yoko
Department of Food and Nutrition, Ochanomizu University
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