Effect of application of calcium phosphate cement on titanium screw mini-implants in the cortical bone of dog femurs

概要

論文の詳細を見る
Calcium phosphate cement (CPC) has been used as a bone substitute because it has a good biocompatibility and osteoconductivity. We investigated how CPC affects the quality of bone response around and fixation of titanium implants. Screw-type pure titanium implants 1.2mm in diameter were placed with and without CPC into pre-drilled 1.2mm diameter cavities in the bilateral hind leg femurs of beagle dogs, and the removal torque strength was measured at 3, 6, 9 and 12 weeks. Higher removal torque strengths were achieved for implants with CPC compared to the controls at three weeks post-insertion (p<0.01). These results may indicate that CPC contributes to the early osseous integration of the interface between implant and bone. This information may be important for the clinical application of early loading.