数種の粉末生薬への電子線殺菌の適用(第1報) : 殺菌効果と性状や成分変化についての検討

概要

論文の詳細を見る
Crude drug are contaminated with microorganisms such as fungi and bacteria. In order to reduce the contaminants in the crude drug powders, steam sterilization under high pressure is widely used. This method, however, causes inactivation of the medicinal principle and/or deterioration of their appearance. Recently, sterilization by irradiation has come to be utilized for food and medicinal products. However, it is mostly done with gamma-rays, and the effects and observations obtained with gamma-ray irradiation are often extrapolated to those of electronic irradiation. In the present study, we studied the electron beam sterilization of crude drug powders with microbial contaminants, and examined the possibility of the use of electron beam sterilization to crude drug powders by analyzing the effects of radiation on the variety of microorganisms and chemical components.
日本生薬学会の論文
1999-12-20