サポニン及びサポゲノール(第46報) : 米国産アルファルファ (Medicago sativa L.) 地上部の含有成分 : Dehydrosoyasaponin I の化学構造

概要

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From the aerial part of North American alfalfa, Medicago sativa L. (Leguminosae), a new glucuronide-saponin named dehydrosoyasaponin I (7) and two glycero-glycolipids (8,9) were isolated together with three known glucuronide-saponins, soyasaponin I (6), azukisaponin II (4), and azukisaponin V (5). the structure of dehydrosoyasaponin I has been determined as 3-O-[α-L-rhamnopyranosyl-(1→2)-β-D-galactopyranosyl-(1→2)-β-D-glucuronopyranosyl]soyasapogenol E (7) from the chemical and spectral evidence. Two glycero-glycolipids have been elucidated respectively as 1-O-β-D-galactopyranosyl-2,3-di-O-acyl-D-glycerol, in which the acyl group comprises linolenoyl (90%), linoleoyl (8%), and palmitoyl (2%) residues (8), and 1-O-[α-D-galactopyranosyl-(l→6)-β-D-galactopyranosyl]-2,3-di-O-acyl-D-glycerol, in which the acyl group comprises linolenoyl (85%), linoleoyl (5%), palmitoyl (5%), oleoyl (3%), and stearoyl (2%) residues (9). On the structure elucidation of 9,the lead-tetraacetate degradation method, which is one of selective cleavage methods for the glucuronide linkage in glucuronide-saponins, has been shown to be applicable for the cleavage of the galacturonide linkage in 9.
公益社団法人日本薬学会の論文
1988-06-25