The Physiological Effects and Metabolic Fate of Ethyl α-D-Glucoside in Rat

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概要

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• Physiological effects and metabolic fate of ethyl α-D-glucoside (α-EG) were investigated using Wistar rats. Rats were received tap water, 10% α-EG, 10% glucose, 10% ethanol or 1O% glucose plus 1O% ethanol solution as drinking solution for 30 days, respectively. Drink intake of the rats fed α-EG and glucose solution was significantly higher. Body weight gain in the rats fed α-EG solution showed significant lower value. α-EG was detected from serum and urine of the rats fed α-EG. Serum concentration of HDL- and total cholesterol and hepatic cholesterollevel in the rats fed α-EG were higher than those of the other groups. In conclusion, orally ingested α-EG was absorbed into blood as its intact form, and was excreted in urine without complete re-absorption in renal tubule. Furthermore this study suggested that α-EG increased might affect cholesterol metabolism.

• 岐阜医療科学大学の論文

著者

• Tsuge Haruhito

  College Of Bioscience And Biotechnology Chubu University

• HAYAKAWA Takashi

  Faculty of Applied Biological Science, Gifu University

• MISHIMA Tomoyuki

  School of Health Science, Gifu University of Medical Science

• OZEKI Kenji

  Kanazawa Institute of Technology, Genome Biotechnology Laboratory

• Mishima Tomoyuki

  School Of Health Science Gifu University Of Medical Science 795-1 Nagamine Ichihiraga Seki Gifu 501-

• Ozeki Kenji

  Genome Biotechnology Laboratory Kanazawa Institute Of Technology 3-1 Yatsukaho Hakusan Ishikawa 924-

• Hayakawa Takashi

  The United Graduate School Of Agricultural Science Gifu University 1-1 Yanagido Gifu Gifu 501-1193 J

• Mishima Tomoyuki

  岐阜医療科学大学 保健科学部

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