Ethyl α-D-Glucoside Increases Urine Volume and Causes Renal Morphologic Changes in Rats

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概要

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• Ethyl α-D-glucoside (α-EG) is a peculiar component in sake, a traditional Japanese alcoholic beverage. In this study, morphological changes in kidney and effects on urine excretion by α-EG ingestion were investigated. After the rats were fed with pellet diets containing 10% or 20% α-EG dietary level, α-EG was detected in urine and urine volume showed significant increase (p<0.05). Kidney weights were increased (p<0.05) and renal tubules were dilated in the rats by α-EG ingestion, whereas there was no detectable histopathological damage to renal cells. Plasma uric acid and urea levels were not affected. In conclusion, ingested α-EG was excreted in urine, increasing urine volume. Increase in kidney weight related to renal tubule dilation was observed with α-EG ingestion without deteriorate changes in the renal cells or functions.

• 日本ビタミン学会の論文

著者

• Ozeki Kenji

  General Research Laboratory Ozeki Corp.

• Ozeki Kenji

  General Research Laboratories Ozeki Corp.

• Hayakawa Takashi

  The United Graduate School of Agricultural Science, Gifu University

• Tsuge Haruhito

  College Of Bioscience And Biotechnology Chubu University

• MISHIMA Tomoyuki

  The United Graduate School of Agricultural Science, Gifu University

• KATAYAMA Yumiko

  General Research Laboratory, Ozeki Corporation

• TAKAGI Yoshie

  Faculty of Agriculture, Gifu University

• TSUGE Haruhito

  The United Graduate School of Agricultural Science, Gifu University

• Katayama Yumiko

  General Research Laboratory Ozeki Corporation

• Takagi Yoshie

  Faculty Of Agriculture Gifu University

• Tsuge Haruhito

  The United Graduate School Of Agricultural Scienc:college Of Bioscience And Biotechnology Chubu Univ

• Mishima Tomoyuki

  School Of Health Science Gifu University Of Medical Science 795-1 Nagamine Ichihiraga Seki Gifu 501-

• Ozeki Kenji

  Genome Biotechnology Laboratory Kanazawa Institute Of Technology 3-1 Yatsukaho Hakusan Ishikawa 924-

• Hayakawa Takashi

  The United Graduate School Of Agricultural Science Gifu University 1-1 Yanagido Gifu Gifu 501-1193 J

• Mishima Tomoyuki

  岐阜医療科学大学 保健科学部

• Hayakawa Takashi

  The United Graduate School Of Agricultural Science Gifu University

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