91(PB3-2) B/Eリンクドスキャンマスによる生理活性物質の構造解析(ポスター発表の部)

概要

論文の詳細を見る
Metastable ion measurements have frequently been used to elucidate complex fragmentation pathways. Several methods are available to monitor metastable ions which are not normally detected in a double focussing mass spectrometer. In this study the voltage of the electric sector (E) was varied simultaneously with the magnetic field (B) such that B/E is constant. This linked scan yields all daughter ions from a specified parent ion. A novel antibiotic was isolated from the culture of an intracellular symbiont present in the eggs of the brown planthopper Nilaparvata lugens. This compound has highly specific activity against the white blight pathogen of rice. The proposed structure was deduced from spectroscopic data and the synthesis of several fragments. A series of B/E linked scans in conjunction with accurate mass measurements defined the connectivity of the partial structures established by ^1H-nmr measurements. The origin of several ions which could notreadily be explained was thus clarified.
天然有機化合物討論会の論文
1987-07-25