The relationship between brachial amyotrophic diplegia and cervical spondylosis
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概要
- 論文の詳細を見る
Objective : To examine cervical spondylosis related to a clinical course of brachial amyotrophic diplegia, we compared the clinical characteristics and degree of cervical magnetic resonance imaging (MRI) findings between a motor neuron disease in which weakness and atrophy localized to the bilateral upper limbs (brachial amyotrophic diplegia) (BAD) and other motor neuron diseases : spinal muscular atrophy, progressive bulbar paralysis, amyotrophic lateral sclerosis, etc. Materials and Methods : A group of 26 patients with motor neuron disease were the subjects of the present study because these patients received careful examinations by MRI for cervical spondylosis in the past 5 years. These 26 patients were divided into 2 groups. Group 1 consisted of patients with BAD whose bilateral upper limb weakness continued for more than a year without significant disturbance in the lower limbs, the bulbar (medulla oblongata) or respiratory function. Group 2 consisted of the other cases. Patients were examined for the degree of cervical spondylosis. The severity of cervical spondylosis was classified into 3 degrees : mild (disc protrusion without spinal cord compression), moderate (intermediate type between mild and severe), severe (spinal cord compression and spinal canal stenosis extending to 3 vertebral bodies). Results : There were 6 of 26 patients in Group 1 and 20 patients in Group 2. Cervical spondylosis was observed in 25 cases. The severity of spondylosis in group 1 included : mild (N = 1), moderate (N = 2), severe (N = 3); Group 2 included : none (N = 1), mild (N = 7), moderate (N = 5), severe (N = 7). Among the patients in Group 1, 50% showed severe spondylotic changes; while among those in Group 2, cervical changes were variable. Conclusion : Cervical spondylosis in patients with brachial amyotrophic diplegia tended to be severe and could influence the clinical course.
- 北里大学の論文
- 2006-09-30
著者
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Hamada Junichi
Department of Clinical Pharmacology, Division of Pathological science, Kyoto Pharmaceutical Universi
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FUKUDA Michinari
Department of Rehabilitation, Kitasato University School of Allied Health Sciences
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Hamada Junichi
Department Of Clinical Pharmacology Division Of Pathological Science Kyoto Pharmaceutical University
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Hamada Junichi
Department Of Neurology Kitasato University School Of Medicine
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Sakai Fumihiko
Kitasato Univ. School Of Medicine
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Sakai Fumihiko
Department Of Neurology Kitasato University School Of Medicine
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Sakai Fumihiko
Department Of Medicine (neurology) Kitasato University School Of Medicine
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Takiyama Yoko
Department of Medicine (Neurology), Kitasato University School of Medicine
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Ogino Yutaka
Department of Neurology, Kitasato University East Hospital
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Ogino Mieko
Department of Neurology, Kitasato University East Hospital
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Ogino M
Department Of Neurology Kitasato University School Of Medicine
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Ogino Mieko
Department Of Internal Medicine Kitasato University School Of Medicine.
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Ogino Y
Department Of Neurology Kitasato University School Of Medicine
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Ogino Yutaka
Department Of Internal Medicine Kitasato University School Of Medicine.
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Fukuda Michinari
北里大学 医療衛生学部リハビリテーション学科
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Fukuda Michinari
Department Of Critical Care Medicine Kitasato University Hospital
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Takiyama Yoko
Department Of Neurology Kitasato University School Of Medicine
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Ogino Mieko
Department Of Neurology Kitasato University School Of Medicine
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SAKAI FUMIHIKO
Department of Internal Medicine, School of Medicine, Kitasato University
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