リウマチ性心疾患 : 再考(老研究者の覚え書)

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During 1957 to 1963, the author had experienced many autopsy cases of rheumatic heart disease. The first case was a 15 year-old girl who suffered of rheumatic fever before 3 years and combined valvular disease before 2 years to her dearh due to congestive heart failure. Pathological diagnosis was rheumatic pancarditis consisted of mitral, aortic and tricuspid valvulitis with functional regurgitation of the blood flow, acute myocarditis with Aschoff nodules and fresh pericarditis. The second case was a 20 year-old girl who suffered of rheumatic arthritis before 6 years and valvular disease before 5 years to her heart failure death. Pathological examination revealed healing rheumatic mitral valvulitis with moderate regurgitation and myocarditis with healing Aschoff nodules. The third case was a 25 year-old house wife who suffered of congestive heart failure before 1 year due to mitral stenosis with clinically unknown onset of rheumatic fever. Pathologically healed mitral valvulitis with cusp adhesion and myocardial fibrosis with a trivial remnant of rheumatic inflammation, were diagnosed. The fourth and fifth cases were both 18 year-old boys with rheumatic fever before 5 and 6 years to their heart failure deaths. The autosy diagnosis of both cases was similar one, i.e., healing pancarditis showing protracted healing process of the rheumatic inflammation. The sixth case was a 33 year-old male engineer who suffered of a giant left atrium associated with rheumatic mitral regurgitation and the seventh case was a 42 year-old male professor who had a big ball valve thrombus in the left atrium associated with rheumatic mitral stenosis. Though the incidence of rheumatic heart disease has been decreasing now-a-days in Japan, yet the rheumatic fever in south east Asia, China and many other developing countries is a major problem. Therefore, we must be alert to study further the treatment and prevention of the rheumatic heart disease.
群馬パース大学の論文
2003-03-31

リウマチ性心疾患 : 再考(老研究者の覚え書)

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