長期Mexiletine内服中に4:1伝導の心房粗動を生じたインシュリン非依存型糖尿病の1例

概要

論文の詳細を見る
Mexiletine (300mg/day) was given for 20 months to a non-insulin dependent patient for the treatment of multifocal ventricular extrasystoles. The patient developed atrial flutter with 4:1 conduction, and the flutter disappeared with the discontinuation of mexiletine. The cause has not been established, and the myocarditis cannot be rouled out. However, no sign of inflammation was observed. This patient has 1st degree AV blook before taking mexiletine. Complete AV block has been reported in intravenous administration of mexiletine. Today, mexiletine is used as the treatment of chronic painful diabetic neuropathy. Therefore, it is important to make an ECG evaluation occasionally during treatment with mexiletine, particularly in patients with AV block.
北里大学の論文
1989-06-30