新しい二重膜濾過血漿分離交換法(加温式リサキュレイション法 : DFサーモ)の性能と臨床効果(<特集>新しい体外循環治療を学ぶ)

概要

論文の詳細を見る
Therapeutic apheresis with the DF Thermo mode (a warming recirculation method), which is categorized as a method of Double Filtration Plasmapheresis (DFPP), is generally clinically performed for patients who suffer from familial hyper-cholesterolemia (FH), arteriosclerosis obliterans (ASO) and so on. The DF Thermo mode is characterized by a plasma fractionation process that consists of a recirculation circuit of concentrated plasma and a warmer to regulate plasma at a physiological temperature. An in vitro study reports that the DF Thermo mode effects a filter performance improvement in the filtered plasma volume and sieving co-efficient of plasma components. The result of this therapy confirmed that a large enough amount of LDL was removed in the FH patients. For the ASO patients, such improvements as a rise in the temperature of lower limbs, an improvement of the pulse wave and a size reduction of the skin ulcer were observed. These positive results seemed to originate in the improvement of the precapillary circulation and show the effectiveness of this therapy.
日本アフェレシス学会の論文
2005-10-31