水道水の衛生化学的研究次亜塩素酸の人血球の機能にあたえる影響について

概要

論文の詳細を見る
As a model experiment for the study of the effect of free chlorine in supplying water on living organisms, effect of hypochlorite on the functions of human blood cells was examined. It was thereby revealed that human erythrocytes were readily hemolyzed by hypochlorite in a concentration as small as 1 ppm and that their agglutinability with certain phytohemagglutinins was clearly enhanced by their treatment with hypochlorite. Further, the blastogenesis of human peripheral lymphocytes in the culture with PHA-M was somewhat facilitated in the presence of hypochlorite in the cutture medium. These results can be explained by the assumption that hypochlorite modifies the surface structure of human blood cells so as to make the receptor sites on the cell surface more accessible to phytohemaglutinins.
社団法人日本薬学会の論文
1972-02-29