An Interpretation of the Hill Equation : Time Course of Diuretic Response after Furosemide Administration in Man
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概要
- 論文の詳細を見る
Response function, which correlates pharmacologic response intensity and the drug concentration, is defined assuming that the biophase (or the site of action) is consisted of the elements responsive to the drug, each of which is in a responding or non-responding state depending on the drug concentration in the biophase. The Hill equation, which has been widely used without a definite rationale, for correlation between pharmacologic response intensity and drug concentration is revealed as an approximate equation of the response function. Diuretic data obtained after administration of furosemide and reported previously are used for conformity assessment of the response function.
- 公益社団法人日本薬学会の論文
著者
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KOIZUMI Tamotsu
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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Koizumi Tamotsu
Faculty Of Pharmaceutical Science Toyama Medical And Pharmaceutical University
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Koizumi Tamotsu
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University:(present Address)dep
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Zhu Jiabi
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University:(present Address)dep
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Zhu Jiabi
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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