Preparation and Cyclodehydration of β-Arylaminocrotonaldehyde

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概要

• 論文の詳細を見る

• β-Arylaminocrotonaldehydes (3) were prepared by alkaline hydrolysis of 1-arylamino-3-arylimino-1-butenes (2). On treatment with sulfuric acid, β-anilinocrotonaldehyde (3b) and p-methyl- (3a), m-chloro- (3c), and p-chloro- (3d) derivatives were cyclodehydrated to give the corresponding quinaldines in quantitative yields. The protonation of 3 was proved to take place at the oxygen atom on the basis of spectral evidence.The mechanism of the cyclodehydration is discussed.

• 社団法人日本薬学会の論文
• 1986-02-25

著者

• 尾能 満智子

  東邦大薬

• 尾能 満智子

  School Of Pharmaceutical Sciences Toho University

• 等々力 玲子

  School of Pharmaceutical Sciences, Toho University

• 田村 眞造

  School of Pharmaceutical Sciences, Toho University

• 田村 眞造

  School Of Pharmaceutical Sciences Toho University

• 田村 真造

  東邦大学 薬

• 等々力 玲子

  School Of Pharmaceutical Sciences Toho University

• Todoriki R

  Toho Univ. Chiba Jpn

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