SIMULTANEOUS DETERMINATION OF PHENYTOIN AND PHENOBARBITAL IN SERUM BY SPIN IMMUNOASSAY
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概要
- 論文の詳細を見る
We describe a spin immunoassay in which the two antiepileptic agents, phenytoin and phenobarbital, are measured simultaneously in a single run. The method involves labeling the two respectively with ^<15>N-and ^<14>N-nitroxide whose ESR peaks do not overlap each other. With 2 μl of serum, the smallest measurable concentration for either drug is 1.25 mg/l. Results of this dual assay compare well with those of conventional assays.
- 公益社団法人日本薬学会の論文
- 1984-04-25
著者
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細川 幹夫
Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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佐用 博照
Faculty of Pharmaceutical Sciences, Kobe-Gakuin University
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細川 幹夫
Faculty of Pharmaceutical Sciences, Kobe-Gakuin University
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佐用 博照
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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