Membrane Potential and Permeability Coefficient of Cellulose Membrane dyed with Congo Red

概要

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Visking cellulose tubing was dyed with various concentrations of Congo Red in order to change the charge density of the membrane. Sodium chloride solutions of different concentrations were placed in the two chambers of a cell divided by the membrane, and the membrane potential and the membrane permeability coefficient were measured at 34℃. The results obtained were analyzed on the of basis theoretical equations for membrane potential and membrane permeability coefficient derived on the basis of nonequilibrium thermodynamics. As the charge density of the membrane increased with the amount of Congo Red in the membrane (mol/cm^3), Congo Red adsorbed on the membrane partly dissociates, into a cation which enters the aqueous solution and a residual anion which remains on the membrane. From measurements of the porosity of the membrane, it was concluded that bound water in the membrane was displaced by Congo Red.
公益社団法人日本薬学会の論文
1983-04-25