A New Phosphatase produced by Streptomyces yokosukanensis
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概要
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The cultured filtrates of Streptomyces were screened for the anti-thymidine kinase activity using the homogenate of Yoshida sarcoma cells and (methyl-^3H)-thymidine to obtain antitumor antibiotics. The active component produced by Streptomyces yokosukanensis was isolated and determined to be a new acid phosphatase (E.C. 3.1.3.2.). Production, isolation, purification, effect of pH on the activity, stability, effect of temperature on the activity, effect of inhibitors on the activity and substrate specifity are described.
- 公益社団法人日本薬学会の論文
- 1972-10-25
著者
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福田 頴穂
Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine
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浅野 健治
Central Research Laboratory Kobayashi Pharmaceutical Co. Ltd.
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福田 頴穂
Pharmaceutical Institute, Hiroshima University School of Medicine
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中村 昭四郎
Pharmaceutical Institute, Hiroshima University School of Medicine
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福田 頴穂
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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浅野 健治
Pharmaceutical Institute, Hiroshima University School of Medicine
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中村 昭四郎
Institute Of Pharmaceutical Sciences
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