Solution Conformation of Ginseng Tetrapeptide H-L-Val-γ-D-Glu-D-Arg-Gly-OH
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概要
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The ginseng tetrapeptide H-L-Val-γ-D-Glu-D-Arg-Gly-OH (1) was synthesized using a solution-phase methodology, and its solution conformation in dimethyl sulfoxide (DMSO)-d_6 was determiend by a combination of NMR and computational techniques with the DADAS90 program. This compound has a rigid backbone based on three intramolecular hydrogen bonds between D-Arg NH and L-VAL CO, between Gly NH and D-Glu CO, and between Gly NH and Gly CO.
- 公益社団法人日本薬学会の論文
- 1998-04-15
著者
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YAGI Akira
Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
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Yagi Akira
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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Ishizu Takashi
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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Fujiwara Masako
Analytical Engineering Department Jeol Datum Ltd.
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Fujiwara Masako
Analytical Instruments Division Jeol Ltd.
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Yagi Akira
Faculty Of Pharmaceutical Sciences Kyushu University
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NOGUCHI Shunsaku
Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
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Noguchi Shunsaku
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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