Enantiomer-Differentiating Ability of Cyclo(L-Phe-L-Pro)_4 Having a Rigid Skeleton for Phenylalanine Methylester Hydrochloride
スポンサーリンク
概要
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The formation constant of the 1 : 1 complex of cyclo(L-Phe-L-Pro)_4 (1) with L-PheOMe・HCl was about 13.2 times that of the complex with D-PheOMe・HCl. The 1 : 1 complex of 1 with L-PheOMe・HCl formed three intermolecular hydrogen bonds between Pro^2 CO, Phe^1 CO and the amino group, and Phe^2 NH and the carbonyl group, whereas that with D-PheOMe・HCl formed only one between Phe^1 CO and the amino group.
- 公益社団法人日本薬学会の論文
- 1997-07-15
著者
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Ishizu Takashi
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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NOGUCHI Shunsaku
Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
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Noguchi Shunsaku
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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