攪拌による菌糸内ヌクレオチドの漏出を伴う菌糸増殖の動力学 : 糸状菌の液内培養における菌糸に与える攪拌の影響に関する研究 (第4報)

概要

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It has been reported by the authors that intracellular low molecular RNA-related nucleotides leaked from mycelia on agitation of mycelial suspension and in aeration-agitation culture of Mucor javanicus NI1051. Further, the rate of leakage of the low molecular nucleotides, Δ_<260>, in mycelial suspension has been proposed as a standard for hte intensity of agitation shock on mycelia.In aeration-agitation culture of the mold, the periodical changes of intracellular and leaked nucleic acid related substances during growth were measured, and it was found that the growth rate depended on the rate of synthesis of high molecular nucleic acid related substances and the rate of leakage of low molecular nucleotides. The ratio of leaked nucleotides to total nucleic acid related substances in the culture system and the relationship between rate of leakage of low molecular nucleotides in suspension system and that in culture system were also investigated. From these results, an equation of the specific growth rate of the mold was derives as a function of Δ_<260>.
社団法人日本生物工学会の論文
1975-01-25