糸状菌菌糸に与える攪拌の衝撃の影響を軽減したジャーファーメンター : 糸状菌の液内培養における菌糸に与える攪拌の影響に関する研究 (第6報)

概要

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Studies were made on the design of a jar fermenter for filamentous microorganisms in which oxygen supply was effective and agitation shock on mycelia was mild; the jar fermenter having a paddle impeller was mainly examined. Shape of the impeller, its location in the jar fermenter, necessity for baffle plates and the system of oxygen supply were decided on the basis of the measurements of volumetric oxygen-transfer coefficient, agitator power and intensity of agitation shock on mycelia (ΔE_<260>). It was found that a jar fermenter having a modified paddle impeller, no baffle plates and no sparger was most suitable. In this fermenter, oxygen was supplied by the introduction of air via the vortex formed at the liquid surface. Under conditions giving the same oxygen tranfer rate, agitator power and agitation shock on mycelia in this fermenter were not so great as those in a conventional fermenter having a flat-blade turbine impeller, four beffle plates and a sparger.In the culture of Mucor javanicus under aeration-agitation conditions giving the same oxygen transfer rate, normal growth due to small agitation shock was obtained in this fermenter, but not in the conventional fermenter.
社団法人日本生物工学会の論文
1975-03-25