懸濁菌糸からの核酸関連物質の漏出過程に及ぼすかく拌の影響 : 糸状菌の液内培養における菌糸に与えるかく拌の影響に関する研究(第7報)

概要

論文の詳細を見る
Experiments were made in order to clarify the mechanism of the remarkable leakage of intracellular nucleic acid-related substances observed on mechanical agitation of mycelial suspension. As reported previously, the leakage occurred through two processes, namely, the degradation of intracellular high molecular nucleic acid-related substances (HN) to low molecular ones (LN) and the permearion of intracellular LN through the surface layer of mycelia.In the present report, the following facts were demonstrated. Agitation has a direct effect on the latter process. Permeation did not occur through a biochemical system which promoted the permeation of LN, but by diffusion. Therefore, it was suggested that the direct effect of agitation on the permeation was to decrease mass-transfer resistance in the surface layer of mycelia and/or in the liquid film around mycelia.
社団法人日本生物工学会の論文
1978-01-25