磁性微粒子の生物工学・医療工学への応用

概要

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Magnetic particles have been used in the field of biotechnology for more than 20 years, and medical applications have also been proposed. Such particles can move toward the way their magnetic gradient becomes steep. Because of this feature, they have been frequently used for separation of specific cells and correct delivery of drug. Heat generation based on hysteresis loss is another important characteristic and the particles have been used to generate heat for intracellular hyperthermia. In addition, they themselves affect the magnetic gradient in a magnetic field and those can be used as a contrast enhancement reagent for magnetic resonance imaging (MRI). Because of the variety of applications, they are known by various names: magnetic microspheres, magnetic supports, magnetic nanospheres, and magnetic fluids. In this article, magnetic particles alone are used and their applications are reviewed, especially in the field of medical engineering.
社団法人日本磁気学会の論文
2001-06-01