Anti-inflammatory Compounds from the Bitter Mushroom, Sarcodon scabrosus(Organic Chemistry)
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概要
- 論文の詳細を見る
A bioassay-guided purification procedure from the methanol extract of Sarcodon scabrosus led to the isolation of several anti-inflammatory compounds : sarcodonin A (1) and G (2), and related compounds (3, 4 and 5). We named these related compounds neosarcodonin A (3), B (4) and C (5) and elucidated their structures on the basis of spectral data. Topical application of each of these compounds to mouse ears suppressed TPA-induced inflammation. Neosarcodonin C (5) exhibited the highest activity and inhibited the TPA-induced edema on mouse ears by up to 87% with a 200-μg application.
- 社団法人日本農芸化学会の論文
- 2002-01-23
著者
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Hirota Mitsuru
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
-
Shibata Hisao
Department Of Agricultural Chemistry Faculty Of Agricultural Shinshu University
-
Morimura Keiji
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
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