Improved Synthesis of the C_8-C_<23> Segment of Aplysiatoxins via Asymmetric Dihydroxylation of the Chiral Homoallylic Alcohol
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概要
- 論文の詳細を見る
Important intermediate 2 of the segment (3) possessing four sequential asymmetric centers (C_9-C_12) of aplysiatoxins was synthesized via dihydroxylation of 5 in only 7 steps from methyl (S)-3-hydroxy-2-methylpropionate. Another promising compound (10a) was also synthesized in only 6 steps via asymmetric dihydroxylation of chiral homoallylic alcohol 4 as the key step.
- 社団法人日本農芸化学会の論文
- 1998-03-23
著者
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TOSHIMA Hiroaki
Department of Bioresource Science, College of Agriculture, Ibaraki University
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ICHIHARA Akitami
Department of Bioscience and Chemistry, Faculty of Agriculture, Hokkaido University
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Toshima Hiroaki
Department Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Ichihara Akitami
Department Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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ICHIHARA Akitami
Department of Agricultural Chemistry, Faculty of Agriculture, Hokkaido University
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