Identification of the Essential Regions for LukS- and HγII-Specific Functions of Staphylococcal Leukocidin and γ-Hemolysin

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概要

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• Staphylococcal leukocidin and γ-hemolysin consist of LukF and LukS for leudocidin and LukF and HγII for γ-hemolysin. To identify the pivotal domain(s) of LukS and HγII responsible for their specific cytolytic activities, a series of chimeric genes (lukS/hlg2) were constructed and expressed in Escherichia coli. The results indicate that the C-terminal 24-residue and the N-terminal 57-residue segments of LukS and HγII, respectively, are the essential regions for the LukS and HγII functions.

• 社団法人日本農芸化学会の論文
• 1995-08-23

著者

• Nariya Hirofumi

  Department Of Applied Biological Chemistry Faculty Of Agriculture Tohoku University

• Kamio Yoshiyuki

  Department Of Agricultural Chemistry Tohoku University

関連論文

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