Identification of the Essential Regions for LukS- and HγII-Specific Functions of Staphylococcal Leukocidin and γ-Hemolysin
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概要
- 論文の詳細を見る
Staphylococcal leukocidin and γ-hemolysin consist of LukF and LukS for leudocidin and LukF and HγII for γ-hemolysin. To identify the pivotal domain(s) of LukS and HγII responsible for their specific cytolytic activities, a series of chimeric genes (lukS/hlg2) were constructed and expressed in Escherichia coli. The results indicate that the C-terminal 24-residue and the N-terminal 57-residue segments of LukS and HγII, respectively, are the essential regions for the LukS and HγII functions.
- 社団法人日本農芸化学会の論文
- 1995-08-23
著者
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Nariya Hirofumi
Department Of Applied Biological Chemistry Faculty Of Agriculture Tohoku University
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Kamio Yoshiyuki
Department Of Agricultural Chemistry Tohoku University
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