Brain Abscess and Glioblastoma Identified by Combined Proton Magnetic Resonance Spectroscopy and Diffusion-Weighted Magnetic Resonance Imaging : Two Case Reports

概要

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The differential diagnosis between brain abscesses and necrotic tumors such as glioblastomas is sometimes difficult to establish by conventional computed tomography and magnetic resonance imaging. Combined proton magnetic resonance spectroscopy ( 1^H-MRS) and diffusion-weighted magnetic resonance imaging (DWI) were used to establish the preoperative diagnosis of brain abscess and glioblastoma. DWI visualized the brain abscess as a homogeneous hyperintense lesion and 1^H-MRS revealed the presence of acetate, lactate, and amino acids and the absence of the normal brain components. DWI sometimes shows glioblastoma as a hyperintense lesion, but 1^H-MRS reveals markedly increased lactate and decreased N-acetyl-aspartate. Combined DWI and 1^H-MRS findings can distinguish brain abscess and glioblastoma.
日本脳神経外科学会の論文
2002-08-15