Regional Left Ventricular Myocardial Contraction Abnormalities and Asynchrony in Patients With Hypertrophic Cardiomyopathy Evaluated by Magnetic Resonance Spatial Modulation of Magnetization Myocardial Tagging
スポンサーリンク
概要
- 論文の詳細を見る
Global ventricular(LV)pump function is generally preserved in patients with hypertrophic cardiomyopathy(HCM). However, it is unknown whether regional myocardial contractility is impaired, especially in nonhypertrophied regions. The purpose of this study was to evaluate regional LV myocardial contraction in patients with HCM using magnetic resonance(MR)spatial modulation of magnetization(SPAMM)myocardial tagging. The study group comprised 20 patients with asymmetric septal hypertrophy(HCM group)and 16 age-matched normal patients(control group), and data were collected using transthoracic M-mode and 2-dimensional echocardiography, and MR SPAMM myocardial tagging. The systolic strain ratio, maximum systolic strain velocity, and time from end-diastole to maximum systolic strain(ΔT)in the anterior, ventricular septal, inferior and lateral regions for 2 LV short-axis sections at the levels of the chordae tendineae and papillary muscles were measured at 50-ms intervals by MR myocardial tagging. The end-diastolic anterior and ventricular septal wall thicknesses and LV mass index were significantly different between the HCM and control groups. The systolic strain ratio for all 4 walls, particularly the anterior and ventricular septal regions, was significantly lower in the HCM group. In the HCM group, the maximum systolic strain velocity was significantly lower and ΔT was significantly shorter for all 4 walls, particularly the anterior and ventricular septal regions. The standard deviation for the ΔT, calculated from the ΔT for the 8 regions of the 2 LV short-axis sections, was significantly greater in the HCM group. In conclusion, regional LV myocardial contraction is impaired in both hypertrophied and nonhypertrophied regions, and systolic LV wall asynchrony occurs in patients with HCM.
- 社団法人日本循環器学会の論文
- 1999-05-20
著者
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Ito S
Department Of Digestive And Cardiovascular Medicine University Of Tokushima Graduate School
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Iuchi Arata
Cardiovascular Section Higashi Tokushima National Hospital National Hospital Organization
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Onose Yukiko
The Second Department of Internal Medicine, School of Medicine, The University of Tokushima
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Harada Masafumi
Department of Radiology, School of Medicine, University of Tokushima
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Takeuchi Y
Kagawa Prefectural Cancer Detection Center
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NISHITANI Hiromu
Department of Radiology, School of Medicine, The University of Tokushima
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ITO SUSUMU
Second Department of Internal Medicine, School of Medicine, University of Tokushima
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Tabata Tomotsugu
Department Of Digestive And Cardiovascular Medicine The University Of Tokushima Graduate School Of M
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Oki Takashi
Second Department of Internal Medicine, University of Tokushima
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Taoka Yoshiaki
Kagawa Prefectural Cancer Detection Center
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Mishiro Yuichiro
Second Department of Internal Medicine
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Iuchi Arata
Internal Medicine, Tokushima Prefectural Miyoshi Hospital
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Tabata Tomotsugu
Second Department of Internal Medicine
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Yamada Hirotsugu
Second Department of Internal Medicine
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Abe Miho
Second Department of Internal Medicine
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Onose Yukiko
Second Department of Internal Medicine
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Taoka Yoshiaki
Department of Radiology, School of Medicine, The University of Tokushima
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Mishiro Yuichiro
Mishiro Cardiomedical Clinic
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Iuchi Arata
Internal Medicine Tokushima Prefectural Miyoshi Hospital
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Onose Yukiko
The Second Department Of Internal Medicine School Of Medicine The University Of Tokushima
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Oki T
Cardiovascular Section Higashi Tokushima National Hospital National Hospital Organization
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Taoka Yoshiaki
Department Of Radiology School Of Medicine The University Of Tokushima
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Mishiro Yuichiro
Mishiro Clinic
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Nishitani Hiromu
Department Of Radiology Institute Of Health Biosciences The University Of Tokushima Graduate Schoo
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Tabata Tomotsugu
The Second Department Of Internal Medicine School Of Medicine University Of Tokushima
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Harada Masafumi
Department Of Health Science And Clothing Environment Faculty Of Human Life And Environment Nara Wom
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Harada Masafumi
Department Of Chemistry Faculty Of Science Kyoto University
-
Oki Takashi
Second Department Of Internal Medicine
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Ito Susumu
Second Department Of Internal Medicine School Of Medicine University Of Tokushima
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Harada Masafumi
Department Of Radiologic Science And Technology Institute Of Health Biosciences University Of Tokushima Graduate School
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