Effectiveness of Revascularization Surgery Evaluated by Proton Magnetic Resonance Spectroscopy and Single Photon Emission Computed Tomography

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概要

• 論文の詳細を見る

• 脳虚血症例(n=26)に対して血行再建前後に1^H-MRSと^<99m>Tc-HMPAOによるSPECTを施行し, 脳循環代謝の改善を評価した. 術前の1^H-MRSで手術側のNAA/Cho, NAA/Crが低値を示したA群(n=12)ではSPECTでも手術側の脳血流は有意に低値を示した. A群の12例中5例では術後3-6ヵ月目の1^H-MRSでNAA/Cho, NAA/Crが改善し, そのうち4例は脳血流も改善した. 術前の1^H-MRSて左右差を認めなかったB群(n=9)では術後の1^H-MRS SPECTでも有意の変化を認めなかった. 術前の1^H-MRSで手術側のNAA/Cho, NAA/Crが上昇していたC群(n=5)では術後2例で1^H-MRS上の, 1例でSPECT上の変化を認めた. 1^H-MRSはSPECTと比較することにより血行再建の効果を判定する上で有用な情報を提供すると思われた.

• 日本脳神経外科学会の論文
• 1996-08-15

著者

• MATSUMOTO Keizo

  徳島大学脳神経外科

• UEDA Shin

  徳島大学脳神経外科

• 宇野 睾明

  徳島大学脳神経

• Harada Masafumi

  Departments Of Radiology School Of Medicine The University Of Tokushima

• Hondo Hideki

  徳島大学脳神経

• Harada Masafumi

  Department Of Health Science And Clothing Environment Faculty Of Human Life And Environment Nara Wom

• Harada Masafumi

  Department Of Chemistry Faculty Of Science Kyoto University

• Ueda Shin

  徳島大学脳神経

• Matsumoto Keizo

  徳島大学脳神経

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