SKIN SENSITIZATION POTENCIES AND ANTIGENICITY OF FORMALDEHYDE AND GLUTARALDEHYDE IN GUINEA PIGS
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 1994-11-30
著者
-
TSUDA Mitsuhiro
Division of Pharmacology, National Institute of Health Sciences
-
Kitamura Y
Division Of Pathology National Institute Of Health Sciences
-
Kaniwa M
Div. Medical Devices National Institute Of Health Sciences
-
Kaniwa Masa-aki
Division Of Medical Devices National Institute Of Health Sciences
-
Tsuda Mitsuhiro
Division Of Pharmacology National Institute Of Health Sciences
-
MOMMA Junko
Division of Toxicology, Biological Safety Research Center, National Institute of Health Sciences
-
SEKIGUCHI Hiromi
Division of Toxicology, Biological Safety Research Center, National Institute of Health Sciences
-
MOMMA Junko
Div.of Toxicolo.
-
Tsuda Mitsuhiro
Div.of Toxicology
-
Tsuda Mitsuhiro
Divisions Of Toxicology And Pharmacology National Institute Of Health Sciences
-
KANAZAWA Yukiko
Dept. Biochem. Toxicol., Showa Univ.
-
Kurokawa Y
Division Of Cellular & Molecular Toxicology National Institute Of Health Sciences
-
KAWASAKI Yasushi
Div.of Toxicol., National Institute of Health Sciences
-
KUROKAWA Yuji
Div.of Toxicol., National Institute of Health Sciences
-
Tsuda Mitsuhiro
Division Of Pharmacology And Biological Safety Research Center National Institute Of Health Sciences
-
Momma Junko
Division Of Toxicology Biological Safety Research Center National Institute Of Health Sciences
-
Kawasaki Yasushi
National Institute Of Health Sciences
-
SEKIGUCHI Hiromi
Div.of Toxicology, National Institute of Health Sciences
-
KANIWA Masa-aki
Div.of Medical Device, National Institute of Health Sciences
-
Kawasaki Yasushi
Div.of Toxicol. National Institute Of Health Sciences
-
Sekiguchi Hiromi
Division Of Toxicology Biological Safety Research Center National Institute Of Health Sciences
-
Kanazawa Yukiko
Dept. Biochem. Toxicol. Showa Univ.:hatano Res. Inst. Fdsc
-
Kanazawa Yukiko
Dept.of Pharmacology And Toxicology Hatano Research Institute Food & Drugs Safety Center
-
Momma Junko
Compliance Review Department The Organization For Drug Adr Relief R&d Promotion And Product Revi
関連論文
- Enhancement of esophageal carcinogenesis in acid reflux model rats treated with ascorbic acid and sodium nitrite in combination with or without initiation
- In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- In vivo mutagenicity and oxidative DNA damage in the livers of gpt delta mice treated with flumequine(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting)
- Catechol enhanced mice hepatotoxicity treated with acetaminophen(Liver, Alimentary system, Proceedings of the 32nd Annual Meeting)
- Lack of Initiating Activity of Kojic Acid on Hepatocarcinogenesis in F344 Rats
- Electron Microscopical Evidence of the Protective Function of Thioredoxin (TRX/ADF) Transgene against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced Cellular Toxicity in the Liver and Brain
- Tumorigenic Susceptibility of Catechol on the Gastric Mucosa in rasH2 Mice
- P8-27 Susceptibility to pentachlorophenol, a mouse liver carcinogen in Nrf2-deficient mice(CIRCULATORY SYSTEM-2/ACTIVE OXYGEN)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Lack of Modifying Effect of Glycerol in Pulmonary Carcinogenesis in rasH2 Mice Induced by Urethane or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
- LACK OF MODIFYING EFFECTS OF EUGENOL ON DEVELOPMENT OF LUNG PROLIFERATIVE LESIONS INDUCED BY URETHANE IN TRANS-GENIC MICE CARRYING THE HUMAN PROTOTYPE c-Ha-ras GENE
- P6-43 Screening of chemopreventive agents using a medium-term pancreas carcinogenesis model in hamsters(DRUG METABOLISM/CARCINOGENICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- A possible role of oxidative stress in potassium bromate (KBrO_3) carcinogenesis (ACTIVE OXYGEN) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Promoting Effects of Ethinylestradiol but not Atrazine on N-ethyl-N-nitrosourea-induced Uterine Carcinogenesis in ICR Mice
- Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl) nitrosamine
- Modifying Effects of 2,6-Dimethylaniline on Nasal Carcinogenesis in RasH2 Mice Initiated with 4-Methylnitrosamino)-1-(3-pyridyl)-1-butanone
- Lack of Modifying Effects of 2,6-Dimethylaniline on Lung Carcinogenesis in Transgenic Mice Carrying Human Prototype c-Ha-ras Gene Initiated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
- Lung as a new target in rats of 2-amino-3-methylimidazo[4,5-f]quinoline carcinogenesis : Results of a two-stage model initiated with N-bis(2-hydroxypropyl)nitrosamine
- Molecular Pathological Analysis of Apoptosis Induced in Testicular Germ Cells after a Single Administration of Mono-(2-ethylhexyl) phthalate to F344 Rats
- The expression of Ras-related molecules in DMBA-induced forestomach tumors in rasH2 mice(Carcinogenicity, Proceedings of the 32nd Annual Meeting)
- In vitro genotoxic potential and liver initiation activity of ciprofloxacin(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting)
- Mechanistic study on hepatocarcinogenesis induced by dicyclanil in mice : possible involvement of oxidative stress(Proceedings of the 32nd Annual Meeting)
- Induction of Hepatocellular Proliferative Lesions in CBA Mice by a 26-week Dietary Administration of Kojic Acid
- Absence of DNA Damage in Comet Assay and Liver Initiation Activity of Cinnamaldehyde
- O-16 Analysis of gene expression profiles of forestomach tumors in rasH2 mice initiated with N-ethyl-N-nitrosourea(ENDOCRINE SYSTEM/DEVELOPMENT AND REPRODUCTION/CARCINOGENICITY/TOXICOGENOMICS)(GENERAL SESSION BY ORAL PRESENTATION)(Proceedings of the 31st
- Enigma of oxidative stress in benzene induced hematotoxicity answered by thioredoxin-overexpression mouse(Blood, Biomarker, Proceedings of the 32nd Annual Meeting)
- A Repeated 28 Days Oral Dose Toxicity Study of Genistein in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.(GENERAL SESSION BY POSTER PRESENTATION)(ENDOCRINE SYSTEM)
- Modifying Effects of Genistein, 4-Nonylphenol and Methoxychlor on N-ethyl-N-nitrosourea-induced Uterine Carcinogenesis in RasH2 Transgenic Mice Harboring a Human Prototype C-Ha-ras Gene
- The Mouse rasH2/BHT Model as an in vivo Rapid Assay for Lung Carcinogens
- Enhancing Effects β-Estradiol 3-Benzoate but Not Methoxychlor on the Promotion/Progression Stage of Chemically-induced Mammary Carcinogenesis in Ovariectomized Rats
- GONADAL TOXICITY OF AN ETHANOL EXTRACT OF PSORALEA CORYLIFOLIA IN A RAT 90-DAY REPEATED DOSE STUDY
- The Utility of N-nitrosamines as Initiators for a 26-Week Rat Two-Stage Nasal Carcinogenesis Model
- P10-09 A Repeated 28 Days Oral Dose Toxicity Study of Methoxychlor in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.
- 3A-08 A Chronic Inhalation Study of p-Dichlorobenzene in the F344 Rat
- "C-1 Reproductive and Developmental Toxicity Studies of Toluene. : II. Effects of inhalation exposure on fertility in rats.
- 306 A 28-DAY REPEATED DOSE TOXICITY TEST OF EUROPIUM AND GADORINIUM IN WISTAR RAT IN COMPARISON WITH LANTHANUM AND YTTRIUM
- 407 A 28-DAY REPEATED DOSE TOXICITY TEST OF LANTHANUM AND YTTRIUM IN WISTAR RAT
- 206 A 28-DAY REPEATED INHALATION TOXICITY TEST OF 2,2,3,3,3-PENTAFLUOROPROPANOL IN F344 RAT
- 21C-03-4 Effects of 2-Mercaptobenzimidazole (MBI) and its methyl derivatives MMBI on rat hepatic drug metabolizing enzymes.
- Analysis of Gene Expression Profile on Uterine Tumorigenesis Initiated with N-ethyl-N-nitrosourea and Inhibited by Ethinylestradiol in rasH2 Mice
- THIRTEEN-WEEK REPEATED DOSE TOXICITY OF RICE BRAN GLYCOSPHINGOLIPID IN WISTAR HANNOVER (GALAS) RATS
- THIRTEEN-WEEK REPEATED DOSE TOXICITY STUDY OF WORMWOOD (ARTEMISIA ABSINTHIUM) EXTRACT IN RATS
- Investigation on liver initiation activity and DNA damages of flumequine in mice.(GENERAL SESSION BY ORAL PRESENTATION)(CARCINOGENICITY)
- "C-6 Evaluation of Rat Hepatotoxicity on Benzimidazole Compounds Using Gap Junctional Intercellular Communication Protein, Connexin 32.
- A SURVEY OF THE VALUES OF CLINICAL CHEMISTRY PARAMETERS OBTAINED FOR A COMMON RAT BLOOD SAMPLE IN NINETY-EIGHT JAPANESE LABORATORIES
- Comparison of the early gene responses of Ahr-activating chemicals using the Percellome system(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
- The development of Chemical Toxicogenomics Database by the "Percellome" system for the mechanism-based toxicology(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
- Toxicity study of Garcinia cambogia extract (3) : Testicular toxicity of Hydroxycitric acid in mice(General toxicity, Proceedings of the 32nd Annual Meeting)
- Bio-molecular model for cancer prevention : Attenuation of oxidative stress by thioredoxin over-expression to reduce the benzene leukemia (BLOOD SYSTEM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Aryl hydrocarbon receptor (AhR) mediated hematotoxicity induced by benzene.(GENERAL SESSION BY ORAL PRESENTATION)(BLOOD SYSTEM & HEMATOLOGY)
- Enhancing effects of carbon tetrachloride on in vivo mutagenicity in the liver of mice fed 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)
- Testicular spermiation failure in rats exposed prenatally to 3,3',4,4',5-pentachlorobiphenyl
- Effects of co-treatment of dextran sulfate sodium and MeIQx on genotoxicity and possible carcinogenicity in the colon of p53-deficient mice
- O-13 Genotoxic potential in vitro and liver initiation activity of norfloxacin(CARCINOGENICITY)(GENERAL SESSION BY ORAL PRESENTATION)(Proceedings of the 31st Annual Meeting)
- O-12 Molecular pathological analyses on hepatocarcinogenesis induced by dicyclanil in mouse two-stage liver carcinogenesis model(CARCINOGENICITY)(GENERAL SESSION BY ORAL PRESENTATION)(Proceedings of the 31st Annual Meeting)
- MECHANISTIC STUDY ON INHIBITION OF SERUM THYROID HORMONE PRODUCTION BY THIOUREA
- THYROID PROLIFERATIVE LESIONS INDUCED BY ANTI-THYROID DRUGS IN RATS ARE NOT ALWAYS ACCOMPANIED BY SUSTAINED INCREASES IN SERUM TSH
- P-103 Collaborative Work to Evaluate Toxicity on Male Reproductive Organs by A 2-Week Repeated-Dose Toxicity Study in Rats : 29)Summary.(Proceedings of the 27th Annual Meeting)
- COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : OVERVIEW OF THE STUDIES
- TIME COURSE OBSERVATION OF THYROID PROLIFERATIVE LESIONS AND SERUM LEVELS OF RELATED HORMONES IN RATS TREATED WITH KOJIC ACID AFTER DHPN INITIATION
- IMMUNOHISTOCHEMICAL STUDIES OF TSH-PRODUCING CELLS IN THE PITUITARY AND EXPRESSION OF GROWTH FACTORS IN THYROIDAL PROLIF-ERATIVE LESIONS IN RATS TREATED WITH THIOUREA AND EXCESS VITAMIN A
- CARCINOGENIC SUSCEPTIBILITY OF HRAS2 TRANSGENIC MICE TO VINYL CARBAMATE AND RAS GENE MUTAIONS IN INDUCED LUNG TUMORS
- "P-42 Protective Effect of Lecithinization-Superoxide Dismutase Against Monocrotaline Induced Lung Injuries
- "P-41 A Morphometric study on the time course change of thyrotroph hypertrophy in the pituitary of rats treated with a goitrogen.
- ABSENCE OF IN VIVO GENOTOXICITY AND LIVER INITIATION ACTIVITY OF DICYCLANIL
- Skin-sensitization potencies of the selected aldehydes in guinea pigs.
- TOXICITY STUDY OF A RUBBER ANTIOXIDANT, 2-MERCAPTOBENZIMIDAZOLE, BY REPEATED ORAL ADMINISTRATION TO RATS
- 2A-13 Reproductive and Developmental Toxicity Studies of Toluene. III. Prenatal and postnatal study by inhalation exposure in rats.
- Lack of Modifying Effects of NNK on Lung Tumorigenesis in Hamsters with Pulmonary Fibrosis Induced by MNUR
- 313 TUMORIGENESIS OF SUBCUTANEOUS IMPLANTATION OF VARIOUS KINDS OF POLYURETHANE(PU) FILMS IN RATS
- A 13-WEEK TOXICITY STUDY OF SIMULTANEOUS ADMINISTRATION OF COCHINEAL AND ALUMINUM POTASSIUM SULFATE IN RATS
- 416 ACUTE AND SUBCHRONIC TOXICITY STUDIES OF 2, 2'-METHYLENEBIS (4-METHYL-6-TERT-BUTYLPHENOL) (MBMBP) IN RATS
- C14 DETECTION OF ALLERGENS IN YELLOW COTTON SWEATERS BY CONTACT DERMATITIS MODEL USING GUINEA PIG
- TOXICITIES OF MICROENCAPSULATED TRIBROMOMETHANE, DIBROMOCHLOROMETHANE AND BROMODICHLOROMETHANE ADMINISTERED IN THE DIET TO WISTAR RATS FOR ONE MONTH
- SIX-MONTH TOXICITY STUDY OF MITOMYCIN C IN MARMOSETS
- DOSE-THRESHOLD FOR THYROID TUMOR-PROMOTING EFFECTS OF ORALLY AMINISTERED KOJIC ACID IN RATS AFTER INITIATION WITH N-bis(2-HYDROXYPROPYL) NITROSAMINE
- CAPACITY FOR INDUCTION OF THYROID PROLIFERATIVE LESIONS BY ANTI-THYROID DRUGS WITH DIFFERENT TOXIC MECHANISMS
- TIME COURSE OBSERVATION OF THYROID PROLIFERATIVE LESIONS AND SERUM TSH LEVELS IN RATS TREATED WITH THIOUREA AFTER DHPN INITIATION
- RELATIONSHIP BETWEEN INDUCTION-DOSES OF THYROID TUMORS BY ANTI-THYROID DRUGS AND PLASMA LEVELS OF T_3, T_4 AND TSH
- Effects of granulocyte-colony stimulatig factor in newborn rats.
- Sample surveillance for clinical pathology testing.
- CHRONIC TOXICITY OF 2,4,6-TRI-TERT-BUTYLPHENOL IN RATS
- C08 TOXICOLOGICAL SIGNIFICANCES OF RED BLOOD CELL (RBC) COUNT AND DISTRIBUTION OF NUCLEATED CELLS IN BONE MARROW
- O-17 Analysis of expression profile of circadian genes(ENDOCRINE SYSTEM/DEVELOPMENT AND REPRODUCTION/CARCINOGENICITY/TOXICOGENOMICS)(GENERAL SESSION BY ORAL PRESENTATION)(Proceedings of the 31st Annual Meeting)
- RESULTS OF A 28-MONTH CHRONIC INHALATION TOXICITY STUDY OF FORMALDEHYDE IN MALE FISHER-344 RATS
- "P-27 Local irritation effects in the nasal cavity and the nasopharyngeal epithelia of the rat treated per os for 10 days with repeated doses of N-(fluorodichloromethylthio) phthalimide ("fluor-folpet").
- Relationship between skin sensitization potencies and chemicophysical properties of aldehydes.
- Lipopolysaccharide-associated increase in serum and urinary nitrite/nitrate levels and hematological changes in rats.
- 28-DAY REPEATED-DOSE ORAL TOXICITY STUDY OF 2-MERCAPTOBENZIMIDAZOLE, A RUBBER ANTIOXIDANT, IN RATS
- A 14-WEEK ORAL TOXICITY STUDY OF TRIBUTOXYETHYL PHOSPHATE(TBEP) IN RATS
- "B-3 Toxicokinetic Study of 2-Mercaptobenzimidazole (MBI) and its Methylated Derivative (MMBI) in Rats after Single Oral-Dose Administration.
- SKIN SENSITIZATION POTENCIES AND ANTIGENICITY OF FORMALDEHYDE AND GLUTARALDEHYDE IN GUINEA PIGS
- COMPARATIVE TOXICOKINETIC STUDY OF RUBBER ANTIOXIDANTS, 2-MERCAPTOBENZIMIDAZOLE AND 2-MERCAPTOMETHYLBENZIMIDAZOLE, BY SINGLE ORAL ADMINISTRATION IN RATS
- 22D-11-3 Increased Liver and Kidney Toxicities in Rats Caused by Co-administration of 2-Mercaptobenzimidazole (MBI) and Lipopolysaccharide (LPS) and Their Toxicokinetics (TK).
- Comparison of Thyroid Toxicity and Toxicokinetics of 2-Mercapto-4-methylbenzimidazole (4MeMBI) and its 5-Methyl Isomer (5MeMBI), Rubber antioxidant, in Rats by Single and Repeated Oral-Dose Administrations
- Endogenous Nitric Oxide Formation Stimulated by LPS in Hypothyroid Rats Induced by 2-Mercaptobenzimidazole (MBI)
- 2C-13 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration - Metabolism and urinary Excretion
- 2C-12 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration.
- Identification of allergenic chemicals in rubber products : Usefullness of investigative procedures using chemical analysis and the Guinea Pig Maximization Test