ポリ塩化ビニル膜からの可塑剤の溶出機構

概要

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We prepared experimentally the polyvinyl chloride (PVC) membrane with the DEHP content of 15.O〜33.3% in order to investigate the mechanism of the leaching of diethylhexyl phthalate (DEHP, a plasticizer of polyvinyl chloride) from a PVC membrane into the solution. The dissolved amount of DEHP was influenced by the content of DEHP in the prepared PVC membrane. The DEHP leaching was not observed at the DEHP content below 20%, but at above 20%, the dissolved amount of DEHP was increased as the DEHP content in the PVC membrane was risen (Fig. 3). The similar phenomenon was observed on the diazepam sorption. It was not occurred at the DEHP content below 20%, while at above 20% diazepam sorbed to the PVC membrane (Fig. 4). These results suggested that the DEHP in the PVC membrane interacted with a PVC molecule at DEHP content below 20%, and at above 20% it was a mixture of a interaction state and a free liquid, and the DEHP dissolution was occurred by the liquid part in the PVC membrane.
日本医療薬学会の論文
1992-12-21